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dc.contributor.author
Kujinga, Prosper
dc.contributor.author
Galetti, Valeria
dc.contributor.author
Onyango, Elizabeth Opiyo
dc.contributor.author
Jakab, Viktor
dc.contributor.author
Buerkli, Simone
dc.contributor.author
Andang'o, Pauline
dc.contributor.author
Brouwer, Inge D.
dc.contributor.author
Zimmermann, Michael B.
dc.contributor.author
Moretti, Diego
dc.date.accessioned
2024-03-22T14:53:52Z
dc.date.available
2018-06-14T06:46:56Z
dc.date.available
2018-06-14T10:54:23Z
dc.date.available
2018-06-22T14:11:55Z
dc.date.available
2018-09-27T16:34:24Z
dc.date.available
2024-03-22T14:53:52Z
dc.date.issued
2018-10
dc.identifier.issn
1368-9800
dc.identifier.issn
1475-2727
dc.identifier.other
10.1017/S1368980018001441
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/269933
dc.identifier.doi
10.3929/ethz-b-000269933
dc.description.abstract
Objective Zn deficiency and diarrhoea are prevalent and may coexist in children living in low-resource settings. Recently, a novel approach for delivering Zn via microbiologically treated, Zn-fortified water was shown to be effective in improving Zn status in West African schoolchildren. We assessed the effectiveness of Zn-fortified, microbiologically purified water delivered as a household intervention on Zn intake, status and morbidity in children aged 2–6 years from rural western Kenya. Design Randomised controlled trial. Intervention included households assigned to water treatment device with (ZFW) or without (FW) Zn delivery capability Setting Rural households in Kisumu, western Kenya. Subjects Children aged 2–6 years. Results The ZFW group had higher dietary Zn intake compared with the FW group. ZFW contributed 36 and 31 % of daily requirements for absorbable Zn in children aged 2–3 and 4–6 years, respectively, in the ZFW group. Consumption of Zn-fortified water resulted in lower prevalence of reported illness (risk ratio; 95 % CI) in the ZFW group compared with the FW group: for cold with runny nose (0·91; 0·83, 0·99; P=0·034) and abdominal pain (0·70; 0·56, 0·89; P=0·003) in the intention-to-treat analysis and for diarrhoea (0·72; 0·53, 0·96; P=0·025) in the per-protocol analysis. We did not detect an effect of treatment on plasma Zn concentration. Conclusions Daily consumption of Zn-fortified, microbiologically treated water results in increased intake of absorbable dietary Zn and may help in preventing childhood infections in pre-school children in rural Africa.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
Cambridge University Press
en_US
dc.rights.uri
http://rightsstatements.org/page/InC-NC/1.0/
dc.subject
Zinc
en_US
dc.subject
Water fortification
en_US
dc.subject
Morbidity
en_US
dc.subject
Plasma zinc concentration
en_US
dc.subject
Pre-school children
en_US
dc.title
Effectiveness of zinc-fortified water on zinc intake, status and morbidity in Kenyan pre-school children: a randomised controlled trial
en_US
dc.type
Journal Article
dc.rights.license
In Copyright - Non-Commercial Use Permitted
dc.date.published
2018-06-07
ethz.journal.title
Public Health Nutrition
ethz.journal.volume
21
en_US
ethz.journal.issue
15
en_US
ethz.journal.abbreviated
Public Health Nutr.
ethz.pages.start
2855
en_US
ethz.pages.end
2865
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.notes
It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
Cambridge
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02070 - Dep. Gesundheitswiss. und Technologie / Dep. of Health Sciences and Technology::02701 - Inst.f. Lebensmittelwiss.,Ernährung,Ges. / Institute of Food, Nutrition, and Health::03957 - Zimmermann, Michael Bruce (emeritus) / Zimmermann, Michael Bruce (emeritus)
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02070 - Dep. Gesundheitswiss. und Technologie / Dep. of Health Sciences and Technology::02701 - Inst.f. Lebensmittelwiss.,Ernährung,Ges. / Institute of Food, Nutrition, and Health::03957 - Zimmermann, Michael Bruce (emeritus) / Zimmermann, Michael Bruce (emeritus)
ethz.date.deposited
2018-06-14T06:47:03Z
ethz.source
SCOPUS
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2018-09-27T16:35:04Z
ethz.rosetta.lastUpdated
2023-02-06T15:56:32Z
ethz.rosetta.exportRequired
true
ethz.rosetta.versionExported
true
ethz.COinS
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