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dc.contributor.author
Hartmann, Fanny E.
dc.contributor.author
McDonald, Bruce
dc.contributor.author
Croll, Daniel
dc.date.accessioned
2018-06-25T11:57:41Z
dc.date.available
2018-06-23T06:12:08Z
dc.date.available
2018-06-25T11:57:41Z
dc.date.issued
2018-06
dc.identifier.issn
0962-1083
dc.identifier.issn
1365-294X
dc.identifier.other
10.1111/mec.14711
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/271872
dc.identifier.doi
10.3929/ethz-b-000271872
dc.description.abstract
The genetic and environmental homogeneity in agricultural ecosystems is thought to impose strong and uniform selection pressures. However, the impact of this selection on plant pathogen genomes remains largely unknown. We aimed to identify the proportion of the genome and the specific gene functions under positive selection in populations of the fungal wheat pathogen Zymoseptoria tritici. First, we performed genome scans in four field populations that were sampled from different continents and on distinct wheat cultivars to test which genomic regions are under recent selection. Based on extended haplotype homozygosity and composite likelihood ratio tests, we identified 384 and 81 selective sweeps affecting 4% and 0.5% of the 35 Mb core genome, respectively. We found differences both in the number and the position of selective sweeps across the genome between populations. Using a XtX‐based outlier detection approach, we identified 51 extremely divergent genomic regions between the allopatric populations, suggesting that divergent selection led to locally adapted pathogen populations. We performed an outlier detection analysis between two sympatric populations infecting two different wheat cultivars to identify evidence for host‐driven selection. Selective sweep regions harboured genes that are likely to play a role in successfully establishing host infections. We also identified secondary metabolite gene clusters and an enrichment in genes encoding transporter and protein localization functions. The latter gene functions mediate responses to environmental stress, including interactions with the host. The distinct gene functions under selection indicate that both local host genotypes and abiotic factors contributed to local adaptation.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
Wiley-Blackwell
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject
adaptation
en_US
dc.subject
ecological genetics
en_US
dc.subject
fungi
en_US
dc.subject
molecular evolution
en_US
dc.subject
natural selection and contemporary evolution
en_US
dc.subject
population genetics — empirical
en_US
dc.title
Genome-wide evidence for divergent selection between populations of a major agricultural pathogen
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 4.0 International
dc.date.published
2018-05-05
ethz.journal.title
Molecular Ecology
ethz.journal.volume
27
en_US
ethz.journal.issue
12
en_US
ethz.journal.abbreviated
Mol Ecol
ethz.pages.start
2725
en_US
ethz.pages.end
2741
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.grant
Genomics of quantitative traits and chromosome instability in Zymoseptoria tritici
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
Oxford
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02350 - Dep. Umweltsystemwissenschaften / Dep. of Environmental Systems Science::02720 - Institut für Integrative Biologie / Institute of Integrative Biology::03516 - McDonald, Bruce / McDonald, Bruce
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02350 - Dep. Umweltsystemwissenschaften / Dep. of Environmental Systems Science::02720 - Institut für Integrative Biologie / Institute of Integrative Biology::03516 - McDonald, Bruce / McDonald, Bruce
ethz.grant.agreementno
155955
ethz.grant.fundername
SNF
ethz.grant.funderDoi
10.13039/501100001711
ethz.grant.program
Projektförderung in Biologie und Medizin (Abteilung III)
ethz.date.deposited
2018-06-23T06:12:25Z
ethz.source
SCOPUS
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2018-06-25T11:57:47Z
ethz.rosetta.lastUpdated
2021-02-15T00:30:46Z
ethz.rosetta.versionExported
true
ethz.COinS
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