Show simple item record

dc.contributor.author
Holper, Lisa
dc.contributor.author
Mühlemann, Thomas
dc.contributor.author
Scholkmann, Felix
dc.contributor.author
Eng, Kynan
dc.contributor.author
Kiper, Daniel C.
dc.contributor.author
Wolf, Martin
dc.date.accessioned
2018-08-21T14:20:03Z
dc.date.available
2017-06-09T09:08:39Z
dc.date.available
2018-08-21T14:20:03Z
dc.date.issued
2010-12
dc.identifier.other
10.1186/1743-0003-7-57
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/29506
dc.identifier.doi
10.3929/ethz-b-000029506
dc.description.abstract
Background Several neurorehabilitation strategies have been introduced over the last decade based on the so-called simulation hypothesis. This hypothesis states that a neural network located in primary and secondary motor areas is activated not only during overt motor execution, but also during observation or imagery of the same motor action. Based on this hypothesis, we investigated the combination of a virtual reality (VR) based neurorehabilitation system together with a wireless functional near infrared spectroscopy (fNIRS) instrument. This combination is particularly appealing from a rehabilitation perspective as it may allow minimally constrained monitoring during neurorehabilitative training. Methods fNIRS was applied over F3 of healthy subjects during task performance in a virtual reality (VR) environment: 1) 'unilateral' group (N = 15), contralateral recording during observation, motor imagery, observation & motor imagery, and imitation of a grasping task performed by a virtual limb (first-person perspective view) using the right hand; 2) 'bilateral' group (N = 8), bilateral recording during observation and imitation of the same task using the right and left hand alternately. Results In the unilateral group, significant within-condition oxy-hemoglobin concentration Δ[O2Hb] changes (mean ± SD μmol/l) were found for motor imagery (0.0868 ± 0.5201 μmol/l) and imitation (0.1715 ± 0.4567 μmol/l). In addition, the bilateral group showed a significant within-condition Δ[O2Hb] change for observation (0.0924 ± 0.3369 μmol/l) as well as between-conditions with lower Δ[O2Hb] amplitudes during observation compared to imitation, especially in the ipsilateral hemisphere (p < 0.001). Further, in the bilateral group, imitation using the non-dominant (left) hand resulted in larger Δ[O2Hb] changes in both the ipsi- and contralateral hemispheres as compared to using the dominant (right) hand. Conclusions This study shows that our combined VR-fNIRS based neurorehabilitation system can activate the action-observation system as described by the simulation hypothesis during performance of observation, motor imagery and imitation of hand actions elicited by a VR environment. Further, in accordance with previous studies, the findings of this study revealed that both inter-subject variability and handedness need to be taken into account when recording in untrained subjects. These findings are of relevance for demonstrating the potential of the VR-fNIRS instrument in neurofeedback applications.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
BioMed Central
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/2.0/
dc.subject
Virtual Reality
en_US
dc.subject
Motor Imagery
en_US
dc.subject
Right Hemisphere
en_US
dc.subject
Virtual Reality System
en_US
dc.subject
Virtual Reality Environment
en_US
dc.title
Testing the potential of a virtual reality neurorehabilitation system during performance of observation, imagery and imitation of motor actions recorded by wireless functional near-infrared spectroscopy (fNIRS)
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 2.0 Generic
ethz.journal.title
Journal of NeuroEngineering and Rehabilitation
ethz.journal.volume
7
en_US
ethz.pages.start
57
en_US
ethz.size
13 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.nebis
005571264
ethz.publication.place
London
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich, direkt::00012 - Lehre und Forschung, direkt::00007 - Departemente, direkt::02140 - Departement Informationstechnologie und Elektrotechnik / Department of Information Technology and Electrical Engineering::02533 - Institut für Neuroinformatik (INI) / Institute of Neuroinformatics (INI)::03454 - Martin, Kevan A.C.
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich, direkt::00012 - Lehre und Forschung, direkt::00007 - Departemente, direkt::02140 - Departement Informationstechnologie und Elektrotechnik / Department of Information Technology and Electrical Engineering::02533 - Institut für Neuroinformatik (INI) / Institute of Neuroinformatics (INI)::03454 - Martin, Kevan A.C.
ethz.relation.isSupplementTo
10.3929/ethz-b-000064553
ethz.date.deposited
2017-06-09T09:08:44Z
ethz.source
ECIT
ethz.identifier.importid
imp59364d9ae1c9f29271
ethz.ecitpid
pub:48961
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2017-07-20T15:21:02Z
ethz.rosetta.lastUpdated
2018-09-01T11:07:09Z
ethz.rosetta.versionExported
true
ethz.COinS
ctx_ver=Z39.88-2004&amp;rft_val_fmt=info:ofi/fmt:kev:mtx:journal&amp;rft.atitle=Testing%20the%20potential%20of%20a%20virtual%20reality%20neurorehabilitation%20system%20during%20performance%20of%20observation,%20imagery%20and%20imitation%20of%20motor&amp;rft.jtitle=Journal%20of%20NeuroEngineering%20and%20Rehabilitation&amp;rft.date=2010-12&amp;rft.volume=7&amp;rft.spage=57&amp;rft.au=Holper,%20Lisa&amp;M%C3%BChlemann,%20Thomas&amp;Scholkmann,%20Felix&amp;Eng,%20Kynan&amp;Kiper,%20Daniel%20C.&amp;rft.genre=article&amp;
 Search via SFX

Files in this item

Thumbnail

Publication type

Show simple item record