Patterns of polymorphism and selection in the subgenomes of the allopolyploid Arabidopsis kamchatica
Briskine, Roman Vladimir
Lischer, Heidi E.L.
Shimizu, Kentaro K.
- Journal Article
Rights / licenseCreative Commons Attribution 4.0 International
Genome duplication is widespread in wild and crop plants. However, little is known about genome-wide selection in polyploids due to the complexity of duplicated genomes. In polyploids, the patterns of purifying selection and adaptive substitutions may be affected by masking owing to duplicated genes or homeologs as well as effective population size. Here, we resequence 25 accessions of the allotetraploid Arabidopsis kamchatica, which is derived from the diploid species A. halleri and A. lyrata. We observe a reduction in purifying selection compared with the parental species. Interestingly, proportions of adaptive non-synonymous substitutions are significantly positive in contrast to most plant species. A recurrent pattern observed in both frequency and divergence–diversity neutrality tests is that the genome-wide distributions of both subgenomes are similar, but the correlation between homeologous pairs is low. This may increase the opportunity of different evolutionary trajectories such as in the HMA4 gene involved in heavy metal hyperaccumulation. Show more
Journal / seriesNature Communications
Pages / Article No.
PublisherNature Publishing Group
Organisational unit09613 - Payne, Joshua (SNF-Professur) / Payne, Joshua (SNF-Professur)
02207 - Functional Genomics Center Zürich / Functional Genomics Center Zürich
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