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dc.contributor.author
Abtahi, Shahab
dc.contributor.author
Driessen, Johanna H.M.
dc.contributor.author
Vestergaard, Peter
dc.contributor.author
van den Bergh, Joop
dc.contributor.author
Boonen, Annelies
dc.contributor.author
de Vries, Frank
dc.contributor.author
Burden, Andrea
dc.date.accessioned
2018-11-23T10:02:37Z
dc.date.available
2018-11-05T12:13:08Z
dc.date.available
2018-11-23T09:40:28Z
dc.date.available
2018-11-23T10:02:37Z
dc.date.issued
2018-12
dc.identifier.issn
1862-3522
dc.identifier.issn
1862-3514
dc.identifier.other
10.1007/s11657-018-0503-z
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/300999
dc.identifier.doi
10.3929/ethz-b-000300999
dc.description.abstract
Summary We investigated the incidence trend in all major osteoporotic fractures for the whole country of Denmark between 1995 and 2010. Hip and other osteoporotic fractures declined for the general population and especially among women. But, we observed some increasing trend among men which needs more attention. Purpose The trend in osteoporotic fractures is varied across the globe, and there is no updated information in the case of Denmark for all major osteoporotic fractures (MOF). Thus, we investigated the incidence rates (IRs) of MOF among 50+ adults in Denmark over the period 1995–2010. Methods A series of cross-sectional analyses was done using the Danish National Health Service Register. Participants were 50+ adults in the full country Denmark with a MOF between 1995 and 2010. Gender- specific IRs of MOF per 10,000 person years (PYs) were estimated, in addition to IRs of individual fracture sites (hip, vertebrae, humerus, and radius/ulna), and women-to-men IR ratios for MOF. Results A general decline was observed in IRs of MOF for the whole population (from 169.8 per 10,000 PYs in 1995, to 148.0 in 2010), which was more pronounced among women. Thirty-one and nineteen percent of decline was observed in hip fracture rates among women and men, respectively. The trend in clinical vertebral fracture was slightly decreasing for women and increasing for men. The women-to-men rate ratio of MOF decreased noticeably from 2.93 to 2.72 during study period. Conclusions We observed declining trends in MOF and hip fracture for both sexes. However, a lower rate of decrease of hip fracture and an increasing trend in vertebral fracture was noticed among men. Considering our observations and the major economic burden which accompanies this devastating disease, more attention should be paid to MOF, especially in men.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
Springer
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject
Osteoporosis
en_US
dc.subject
Osteoporotic fractures
en_US
dc.subject
Epidemiology
en_US
dc.subject
Incidence rates
en_US
dc.title
Secular trends in major osteoporotic fractures among 50+ adults in Denmark between 1995 and 2010
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 4.0 International
dc.date.published
2018-08-27
ethz.journal.title
Archives of Osteoporosis
ethz.journal.volume
13
en_US
ethz.pages.start
91
en_US
ethz.size
7 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.publication.place
London
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02020 - Dep. Chemie und Angewandte Biowiss. / Dep. of Chemistry and Applied Biosc.::02534 - Institut für Pharmazeutische Wiss. / Institute of Pharmaceutical Sciences::09633 - Burden, Andrea / Burden, Andrea
en_US
ethz.date.deposited
2018-11-05T12:13:11Z
ethz.source
FORM
ethz.eth
no
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2018-11-23T09:40:48Z
ethz.rosetta.lastUpdated
2019-01-03T09:39:59Z
ethz.rosetta.versionExported
true
ethz.COinS
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