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dc.contributor.author
Simpson, Caitlin
dc.contributor.author
Lee, Sung Sik
dc.contributor.author
Lee, Chang-Soo
dc.contributor.author
Yamauchi, Yohei
dc.date.accessioned
2019-01-18T14:09:58Z
dc.date.available
2019-01-07T13:28:08Z
dc.date.available
2019-01-18T14:09:58Z
dc.date.issued
2018-12
dc.identifier.other
10.1007/s40588-018-0105-y
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/314054
dc.identifier.doi
10.3929/ethz-b-000314054
dc.description.abstract
Purpose of Review Microfluidic platforms have become valuable tools in a wide variety of research environments. With the ability to allow detailed examination of an array of cell biological processes, their use in the field of virology is becoming progressively more common. This review will discuss the potential applications of microfluidics in viral cell biology and explore the potential of these techniques to alter the way in which we study the biology of infection. Recent Findings In recent years, scientists have utilised microfluidic platforms for detailed study of the viral life cycle. Microfluidic technologies have allowed investigation of viral infectivity, measurement of fusion kinetics, and monitoring of viral responses to neutralising compounds. In addition, microfluidic platforms represent promising new clinical tools with applications in diagnostics and drug screening. Summary Although the potential of microfluidics in virology is beginning to be realised, it has certainly not been fully explored. While not a replacement for macroscale investigative techniques, microfluidic platforms have the potential to be utilised alongside systems biology to provide novel methods of detailed virus study, with unique advantages.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
Springer
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject
Virus microfluidics
en_US
dc.subject
Virus entry
en_US
dc.subject
Viral cell biology
en_US
dc.subject
Fluorescence imaging
en_US
dc.subject
Single particle
en_US
dc.subject
Single-cell analysis
en_US
dc.title
Microfluidics: An untapped resource in viral diagnostics and viral cell biology
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 4.0 International
dc.date.published
2018-08-01
ethz.journal.title
Current Clinical Microbiology Reports
ethz.journal.volume
5
en_US
ethz.journal.issue
4
en_US
ethz.pages.start
245
en_US
ethz.pages.end
251
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.scopus
ethz.publication.place
Cham
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00003 - Schulleitung und Dienste::00022 - Bereich VP Forschung & Wirtschaftsbez. / Domain VP Research & Corporate Relations::02891 - ScopeM / ScopeM
en_US
ethz.date.deposited
2019-01-07T13:28:09Z
ethz.source
FORM
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2019-01-18T14:10:05Z
ethz.rosetta.lastUpdated
2019-01-18T14:10:05Z
ethz.rosetta.exportRequired
true
ethz.rosetta.versionExported
true
ethz.COinS
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