Activation of Primary and Secondary Benzylic and Tertiary Alkyl (sp(3))C-F Bonds Inside a Self-Assembled Molecular Container
Köster, Jesper M.
- Journal Article
Rights / licenseCreative Commons Attribution 4.0 International
Alkyl fluorides are generally regarded as chemically inert. However, several literature examples describe the activation of alkyl (sp3)C-F bonds via strong Brønsted or Lewis acids under harsh conditions. We here report that catalytic amounts of the self-assembled resorcinarene capsule are able to activate alkyl (sp3)C-F bonds under mild conditions (40°C, no strong Brønsted or Lewis acid present). Kinetic measurements display a sigmoidal reaction progress after an initial induction period. Control experiments indicate that the presence of the supramolecular capsule is required for an efficient reaction acceleration. Show more
Journal / seriesFrontiers in Chemistry
Pages / Article No.
Subjectsupramolecular catalysis; molecular capsules; supramolecular chemistry; acid catalysis; elimination
Organisational unit09585 - Tiefenbacher, Konrad / Tiefenbacher, Konrad
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