Small-Molecule Allosteric Triggers of Clostridium difficile Toxin B Auto-proteolysis as a Therapeutic Strategy

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Author
Ivarsson, Mattias E.
Durantie, Estelle
Huberli, Corina
Huwiler, Samuel
Hegde, Chrismita
Friedman, Jillian
Altamura, Fernando
Lu, Jun
Verdu, Elena F.
Bercik, Premysl
Logan, Susan M.
Chen, Wangxue
Leroux, Jean-Christophecc
Castagner, Bastien
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Date
2019-01-17
Type
    Journal Article
Publication status
published
External links
Journal / series
Cell Chemical Biology
Volume
26(1)
Pages / Article No.
17 - 26e13
Publisher
Elsevier
Subject
Clostridium difficile; bacterial toxins; small-molecule drug; allosteric modulator; inositol phosphates; non-antibiotic strategy
Organisational unit
03811 - Leroux, Jean-Christophe / Leroux, Jean-Christophe  
Funding
141263 - Early Auto-processing of Bacterial Toxins as a Therapeutic Approach (SNF)
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Citations
Cited 8 times in Web of Science
Cited 9 times in Scopus
ETH Bibliography
yes
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