Improved Inhibitors of Trypanothione Reductase by Combination of Motifs: Synthesis, Inhibitory Potency, Binding Mode, and Antiprotozoal Activities

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Author
Eberle, Christian
Lauber, Birgit Sophia
Fankhauser, Daniel
Kaiser, Marcel
Brun, Reto
Krauth-Siegel, R. Luise
Diederich, François
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Date
2011-02
Type
  • Journal Article
Publication status
published
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Journal / series
ChemMedChem
Volume
6(2)
Pages / Article No.
292 - 301
Publisher
Wiley
Subject
Antimalarial agents; Structure-based design; Tropical diseases; Trypanocidal agents; Trypanothione reductases
Organisational unit
03344 - Diederich, François  
Notes
Received 3 October 2010, Published online on 16 December 2010.
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Citations
Cited 15 times in Web of Science
Cited 20 times in Scopus
ETH Bibliography
yes
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