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dc.contributor.author
Sarkiri, Maria
dc.contributor.author
Fox, Stephan
dc.contributor.author
Fratila-Apachitei, Lidy E.
dc.contributor.author
Zadpoor, Amir A.
dc.date.accessioned
2019-04-09T08:36:48Z
dc.date.available
2019-04-07T11:33:01Z
dc.date.available
2019-04-09T08:36:48Z
dc.date.issued
2019-03-02
dc.identifier.issn
1422-0067
dc.identifier.other
10.3390/ijms20061407
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/336643
dc.identifier.doi
10.3929/ethz-b-000336643
dc.description.abstract
Clinical use of bioengineered skin in reconstructive surgery has been established for more than 30 years. The limitations and ethical considerations regarding the use of animal models have expanded the application of bioengineered skin in the areas of disease modeling and drug screening. These skin models should represent the anatomical and physiological traits of native skin for the efficient replication of normal and pathological skin conditions. In addition, reliability of such models is essential for the conduction of faithful, rapid, and large-scale studies. Therefore, research efforts are focused on automated fabrication methods to replace the traditional manual approaches. This report presents an overview of the skin models applicable to skin disease modeling along with their fabrication methods, and discusses the potential of the currently available options to conform and satisfy the demands for disease modeling and drug screening.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
MDPI
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject
bioengineered skin
en_US
dc.subject
biofabrication
en_US
dc.subject
skin disease modeling
en_US
dc.subject
standardization
en_US
dc.title
Bioengineered Skin Intended for Skin Disease Modeling
en_US
dc.type
Review Article
dc.rights.license
Creative Commons Attribution 4.0 International
dc.date.published
2019-03-20
ethz.journal.title
International Journal of Molecular Sciences
ethz.journal.volume
20
en_US
ethz.journal.issue
6
en_US
ethz.journal.abbreviated
Int. j. mol. sci.
ethz.pages.start
1407
en_US
ethz.size
18 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
Basel
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02130 - Dep. Maschinenbau und Verfahrenstechnik / Dep. of Mechanical and Process Eng.::02665 - Inst. f. Design, Mat. und Fabrikation::03943 - Meboldt, Mirko / Meboldt, Mirko
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02130 - Dep. Maschinenbau und Verfahrenstechnik / Dep. of Mechanical and Process Eng.::02665 - Inst. f. Design, Mat. und Fabrikation::03943 - Meboldt, Mirko / Meboldt, Mirko
ethz.date.deposited
2019-04-07T11:33:09Z
ethz.source
SCOPUS
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2019-04-09T08:36:58Z
ethz.rosetta.lastUpdated
2022-03-28T22:44:58Z
ethz.rosetta.versionExported
true
ethz.COinS
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