Show simple item record

dc.contributor.author
Zollinger, Adrian
dc.contributor.author
Attin, Thomas
dc.contributor.author
Mohn, Dirk
dc.contributor.author
Zehnder, Matthias
dc.date.accessioned
2019-05-28T16:49:39Z
dc.date.available
2019-05-28T14:05:13Z
dc.date.available
2019-05-28T16:49:39Z
dc.date.issued
2019-05
dc.identifier.other
10.1016/j.heliyon.2019.e01794
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/344433
dc.identifier.doi
10.3929/ethz-b-000344433
dc.description.abstract
Objectives This study aimed to investigate bleaching effects of common endodontic irrigants on human whole blood and blood-stained dentin. Specifically, it was assessed whether sodium hypochlorite at a clinically recommended concentration (2.5% NaOCl) would bleach with similar efficacy as a peroxide-based irrigant at higher molarity (5% H2O2). Furthermore, the effects of a NaOCl-compatible chelator with a high affinity to iron (Dual Rinse HEDP) were investigated. Methods Human whole blood was mixed at a 1:20 ratio with either phosphate-buffered saline, 9% HEDP, 2.5% NaOCl, 2.5% NaOCl containing 9% HEDP, or 5% H2O2. Effects were assessed spectrometrically and photographically. Human dentin specimens were prepared with a methacrylate reservoir for liquids and a polished assessment side over 1 mm dentin thickness. Dentin was stained using human whole blood for 3 weeks and subsequently exposed to the irrigants for 60 min. Measurements were performed in the CIELAB color space. Results were compared using parametric tests with the alpha-type error set to 5%. Results When directly exposed, the solutions containing NaOCl completely discolored the blood, while the 5% H2O2 exerted a bleaching effect without complete dissolution of dissolved matter, and the pure 9% HEDP had no effect at all. The NaOCl solutions bleached blood-stained dentin more efficiently than H2O2 (p < 0.05). Conclusions Under the current conditions, the 2.5% NaOCl solution had a stronger bleaching effect on blood and blood-stained dentin than 5% H2O2. HEDP did not have any direct impact on blood color or NaOCl-derived bleaching.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
Elsevier
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject
Dentistry
en_US
dc.title
Effects of endodontic irrigants on blood and blood-stained dentin
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 4.0 International
dc.date.published
2019-05-23
ethz.journal.title
Heliyon
ethz.journal.volume
5
en_US
ethz.journal.issue
5
en_US
ethz.pages.start
e01794
en_US
ethz.size
6 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.scopus
ethz.publication.place
London
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02020 - Dep. Chemie und Angewandte Biowiss. / Dep. of Chemistry and Applied Biosc.::02516 - Inst. f. Chemie- und Bioingenieurwiss. / Inst. Chemical and Bioengineering::03673 - Stark, Wendelin J. / Stark, Wendelin J.
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02020 - Dep. Chemie und Angewandte Biowiss. / Dep. of Chemistry and Applied Biosc.::02516 - Inst. f. Chemie- und Bioingenieurwiss. / Inst. Chemical and Bioengineering::03673 - Stark, Wendelin J. / Stark, Wendelin J.
en_US
ethz.date.deposited
2019-05-28T14:05:20Z
ethz.source
FORM
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2019-05-28T16:49:52Z
ethz.rosetta.lastUpdated
2020-02-15T19:21:48Z
ethz.rosetta.versionExported
true
ethz.COinS
ctx_ver=Z39.88-2004&amp;rft_val_fmt=info:ofi/fmt:kev:mtx:journal&amp;rft.atitle=Effects%20of%20endodontic%20irrigants%20on%20blood%20and%20blood-stained%20dentin&amp;rft.jtitle=Heliyon&amp;rft.date=2019-05&amp;rft.volume=5&amp;rft.issue=5&amp;rft.spage=e01794&amp;rft.au=Zollinger,%20Adrian&amp;Attin,%20Thomas&amp;Mohn,%20Dirk&amp;Zehnder,%20Matthias&amp;rft.genre=article&amp;rft_id=info:doi/10.1016/j.heliyon.2019.e01794&amp;
 Search print copy at ETH Library

Files in this item

Thumbnail

Publication type

Show simple item record