A new model for drug interactions and optimal drug dosing
dc.contributor.author
Zanderigo, Eleonora
dc.contributor.author
Sartori, Valentina
dc.contributor.author
Sveticic, Gorazd
dc.contributor.author
Bouillon, Thomas
dc.contributor.author
Schumacher, Peter
dc.contributor.author
Curatolo, Michele
dc.contributor.author
Morari, Manfred
dc.date.accessioned
2020-09-10T12:57:12Z
dc.date.available
2017-06-09T11:02:49Z
dc.date.available
2020-09-10T12:56:09Z
dc.date.available
2020-09-10T12:57:12Z
dc.date.issued
2005
dc.identifier.isbn
0-7803-8740-6
en_US
dc.identifier.other
10.1109/IEMBS.2005.1616938
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/34904
dc.description.abstract
Drugs are routinely combined in anesthesia and pain management to obtain an enhancement of the desired effects. However, a parallel enhancement of the undesired effects might take place as well, resulting in a limited therapeutic usefulness. Therefore, when addressing the question of optimal drug combinations, side effects must be taken into account. We propose a new method to study drug interactions considering also their side effects and to identify optimal drug dosing. The model is consistent with clinical knowledge and can explain previously published experimental results, improving our understanding of the characteristics of drug combinations used in clinical practice.
en_US
dc.language.iso
en
en_US
dc.publisher
IEEE
en_US
dc.subject
Drug interactions
en_US
dc.subject
Optimal drug dosing
en_US
dc.subject
Pharmacodynamic modelling
en_US
dc.title
A new model for drug interactions and optimal drug dosing
en_US
dc.type
Conference Paper
dc.date.published
2006-04-10
ethz.book.title
Proceedings of the 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference
en_US
ethz.pages.start
2353
en_US
ethz.pages.end
2356
en_US
ethz.event
27th Annual International Conference of the Engineering in Medicine and Biology Society (IEEE-EMBS 2005)
en_US
ethz.event.location
Shanghai, China
en_US
ethz.event.date
September 1-4, 2005
en_US
ethz.identifier.wos
ethz.identifier.nebis
005216252
ethz.publication.place
Piscataway, NJ
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich, direkt::00012 - Lehre und Forschung, direkt::00007 - Departemente, direkt::02140 - Departement Informationstechnologie und Elektrotechnik / Department of Information Technology and Electrical Engineering::02650 - Institut für Automatik (IfA) / Automatic Control Laboratory (IfA)::03416 - Morari, Manfred (emeritus)
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich, direkt::00012 - Lehre und Forschung, direkt::00007 - Departemente, direkt::02140 - Departement Informationstechnologie und Elektrotechnik / Department of Information Technology and Electrical Engineering::02650 - Institut für Automatik (IfA) / Automatic Control Laboratory (IfA)::03416 - Morari, Manfred (emeritus)
ethz.date.deposited
2017-06-09T11:02:59Z
ethz.source
ECIT
ethz.identifier.importid
imp59364e07af58e30316
ethz.ecitpid
pub:56124
ethz.eth
yes
en_US
ethz.availability
Metadata only
en_US
ethz.rosetta.installDate
2017-07-12T19:04:06Z
ethz.rosetta.lastUpdated
2021-02-15T17:08:53Z
ethz.rosetta.versionExported
true
ethz.COinS
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