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dc.contributor.author
Nair, Ramith R.
dc.contributor.author
Vasse, Marie
dc.contributor.author
Wielgoss, Sebastien
dc.contributor.author
Sun, Lei
dc.contributor.author
Yu, Yuen-Tsu N.
dc.contributor.author
Velicer, Gregory J.
dc.date.accessioned
2019-09-30T08:06:27Z
dc.date.available
2019-09-28T08:35:10Z
dc.date.available
2019-09-30T08:06:27Z
dc.date.issued
2019-09-20
dc.identifier.issn
2041-1723
dc.identifier.other
10.1038/s41467-019-12140-6
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/367075
dc.identifier.doi
10.3929/ethz-b-000367075
dc.description.abstract
Generalist bacterial predators are likely to strongly shape many important ecological and evolutionary features of microbial communities, for example by altering the character and pace of molecular evolution, but investigations of such effects are scarce. Here we report how predator-prey interactions alter the evolution of fitness, genomes and phenotypic diversity in coevolving bacterial communities composed of Myxococcus xanthus as predator and Escherichia coli as prey, relative to single-species controls. We show evidence of reciprocal adaptation and demonstrate accelerated genomic evolution specific to coevolving communities, including the rapid appearance of mutator genotypes. Strong parallel evolution unique to the predator-prey communities occurs in both parties, with predators driving adaptation at two prey traits associated with virulence in bacterial pathogens—mucoidy and the outer-membrane protease OmpT. Our results suggest that generalist predatory bacteria are important determinants of how complex microbial communities and their interaction networks evolve in natural habitats.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
Nature
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.title
Bacterial predator-prey coevolution accelerates genome evolution and selects on virulence-associated prey defences
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 4.0 International
ethz.journal.title
Nature Communications
ethz.journal.volume
10
en_US
ethz.journal.issue
1
en_US
ethz.journal.abbreviated
Nat Commun
ethz.pages.start
4301
en_US
ethz.size
10 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
London
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02350 - Dep. Umweltsystemwissenschaften / Dep. of Environmental Systems Science::02720 - Institut für Integrative Biologie / Institute of Integrative Biology::03939 - Velicer, Gregory J. / Velicer, Gregory J.
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02350 - Dep. Umweltsystemwissenschaften / Dep. of Environmental Systems Science::02720 - Institut für Integrative Biologie / Institute of Integrative Biology::03939 - Velicer, Gregory J. / Velicer, Gregory J.
ethz.date.deposited
2019-09-28T08:35:33Z
ethz.source
SCOPUS
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2019-09-30T08:06:47Z
ethz.rosetta.lastUpdated
2024-02-02T09:27:48Z
ethz.rosetta.versionExported
true
ethz.COinS
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