Integration of Discrete Sensors and Microelectrode Arrays Into Open Microfluidic Hanging-Drop Networks
Abstract
This work presents a new versatile method to integrate discrete sensor chips into open-microfluidic hanging-drop networks. As proof of concept, we integrated an electrical-impedance-spectroscopy (EIS) sensor unit into a hanging-drop platform for monitoring the size of microtissues. The fabrication and assembly method enables the integration of a large variety of silicon-based sensors, such as chemical sensors, biosensors or microelectrode arrays (MEAs), in open-microfluidic hanging-drop networks to perform studies on three-dimensional microtissues. © 2019 IEEE. Show more
Permanent link
https://doi.org/10.3929/ethz-b-000376523Publication status
publishedExternal links
Book title
2019 IEEE 32nd International Conference on Micro Electro Mechanical Systems (MEMS)Pages / Article No.
Publisher
IEEEEvent
Organisational unit
03684 - Hierlemann, Andreas / Hierlemann, Andreas
Funding
171267 - Integration of CMOS sensors and circuits into microphysiological hanging-drop networks (SNF)
694829 - Microtechnology and integrated microsystems to investigate neuronal networks across scales (EC)
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