Automated and enhanced extraction of a small molecule-drug conjugate using an enzyme-inhibitor interaction based SPME tool followed by direct analysis by ESI-MS

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Author
Ghiasikhou, Sahar
Cazzamalli, Samuele
Scheuermann, Jörgcc
Neri, Dariocc
Zenobi, Renatocc
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Date
2019-11
Type
    Journal Article
Publication status
published
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Journal / series
Analytical and Bioanalytical Chemistry
Volume
411(28)
Pages / Article No.
7387 - 7398
Publisher
Springer
Subject
Capillary gap sampler; Solid-phase microextraction; Targeted drug delivery; Small molecule-drug conjugates; Carbonic anhydrase; Acetazolamide
Organisational unit
03430 - Zenobi, Renato / Zenobi, Renato  
03463 - Neri, Dario / Neri, Dario  
Funding
159929 - Soft ionization mass spectrometry for studying noncovalent interactions (SNF)
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