Understanding mAb aggregation during low pH viral inactivation and subsequent neutralization

Wälchli, Ruben; Ressurreição, Mariana; Vogg, Sebastian; Feidl, Fabian; Angelo, James; Xu, Xuankuo; Ghose, Sanchayita; Li, Zheng-Jian; Le Saoût, Xavier; Souquet, Jonathan; Broly, Hervé; Morbidelli, Massimo

doi:10.1002/bit.27237

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Autor(in)

Wälchli, Ruben

Ressurreição, Mariana

Datum

2020-03

Typ

Journal Article

Zitate

37 Zitate in Scopus

ETH Bibliographie

yes

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Publikationsstatus

published

Externe Links

https://doi.org/10.1002/bit.27237

Zeitschrift / Serie

Biotechnology and Bioengineering

Band

117(3)

Seiten / Artikelnummer

687 - 700

Verlag

Wiley

Thema

ANS fluorescence; Downstream processing; Monoclonal antibodies; Protein aggregation; Protein unfolding; Viral inactivation

Organisationseinheit

03451 - Morbidelli, Massimo (emeritus) / Morbidelli, Massimo (emeritus)

Förderung

165917 - Design of Aggregation Processes of Binary Colloids towards Preparation of Nano-Composite Materials (SNF)

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Zitate

37 Zitate in Scopus

ETH Bibliographie

yes

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Understanding mAb aggregation during low pH viral inactivation and subsequent neutralization

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