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dc.contributor.author
Falk V
dc.contributor.author
Hagendorff, Andreas
dc.contributor.author
Doenst, Torsten
dc.contributor.author
Falk, Volkmar
dc.date.accessioned
2020-01-14T09:35:43Z
dc.date.available
2020-01-13T10:38:59Z
dc.date.available
2020-01-14T09:35:43Z
dc.date.issued
2019-08
dc.identifier.issn
2055-5822
dc.identifier.other
10.1002/ehf2.12491
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/389646
dc.identifier.doi
10.3929/ethz-b-000389646
dc.description.abstract
Two recent trials of transcatheter mitral‐valve repair in patients with functional mitral regurgitation (FMR) presented opposing results for the MitraClip® compared to medical therapy alone. The conflicting results gave rise to intensive discussions about assessment of mitral valve regurgitation (MR). A recent editorial viewpoint provided a potential explanation presenting a new pathophysiologic concept. However, the echocardiographic characterization of both trials' patients is inconsistent and the discussed concepts appear to suffer from plausibility weaknesses. It is well conceivable that limitations in the echocardiographic assessment of the trial patients introduced a bias regarding the selection of patients with severe (or less severe) MR that may be a more plausible explanation for the differences in outcome. We here illustrate our viewpoint regarding the two MitraClip trials and also illustrate the difficulties in assessing functional MR properly. It may indeed be “opening Pandora's box”, but we will also make an attempt to provide a solution.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
John Wiley & Sons Ltd.
en_US
dc.rights.uri
http://creativecommons.org/licenses/by-nc/4.0/
dc.title
Echocardiographic assessment of functional mitral regurgitation: opening Pandora's box?
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution-NonCommercial 4.0 International
dc.date.published
2019-07-25
ethz.journal.title
ESC Heart Failure
ethz.journal.volume
6
en_US
ethz.journal.issue
4
en_US
ethz.journal.abbreviated
ESC Heart Fail
ethz.pages.start
678
en_US
ethz.pages.end
685
en_US
ethz.size
8 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.pubmed
31347297
ethz.publication.place
Oxford
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02070 - Dep. Gesundheitswiss. und Technologie / Dep. of Health Sciences and Technology::02540 - Institut für Translationale Medizin / Institute of Translational Medicine::09667 - Falk, Volkmar / Falk, Volkmar
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02070 - Dep. Gesundheitswiss. und Technologie / Dep. of Health Sciences and Technology::02540 - Institut für Translationale Medizin / Institute of Translational Medicine::09667 - Falk, Volkmar / Falk, Volkmar
en_US
ethz.identifier.orcidWorkCode
66892739
ethz.date.deposited
2020-01-13T10:39:07Z
ethz.source
FORM
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2020-01-14T09:35:53Z
ethz.rosetta.lastUpdated
2022-03-29T00:34:30Z
ethz.rosetta.versionExported
true
ethz.COinS
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