Living in a bubble: On chip monitoring of microbial production in lipid vesicles
dc.contributor.author
Jusková, Petra
dc.contributor.author
Schmid, Yannick R.F.
dc.contributor.author
Schmitt, Steven
dc.contributor.author
Held, Martin
dc.contributor.author
Dittrich, Petra S.
dc.date.accessioned
2020-10-21T12:19:21Z
dc.date.available
2020-01-14T07:45:08Z
dc.date.available
2020-01-14T08:36:38Z
dc.date.available
2020-10-21T12:14:02Z
dc.date.available
2020-10-21T12:19:21Z
dc.date.issued
2019
dc.identifier.isbn
978-1-7334190-0-0
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/390031
dc.description.abstract
We present a novel microbial cultivation strategy combined with a microfluidic platform for real-time monitoring of microbial growth and production. Escherichia coli overexpressing the riboflavin (vitamin B2) biosynthetic pathway is encapsulated in giant lipid vesicles (GUVs) and cultivated on-chip. The behavior of cultures under optimum conditions and under antibiotic stress are compared.
en_US
dc.language.iso
en
en_US
dc.publisher
Chemical and Biological Microsystems Society
en_US
dc.subject
Antibiotics
en_US
dc.subject
Microbial cultivation
en_US
dc.subject
Single-cell analysis
en_US
dc.title
Living in a bubble: On chip monitoring of microbial production in lipid vesicles
en_US
dc.type
Other Conference Item
ethz.book.title
23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2019)
en_US
ethz.pages.start
370
en_US
ethz.pages.end
371
en_US
ethz.event
23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2019)
en_US
ethz.event.location
Basel, Switzerland
en_US
ethz.event.date
October 27-31, 2019
en_US
ethz.notes
Poster presentation W023.a
en_US
ethz.grant
Microfluidic device for ultrarapid phenotypic susceptibility testing of pathogenic microbes
en_US
ethz.grant
Engineering of hybrid cells using lab-on-chip technology
en_US
ethz.publication.place
San Diego, CA, USA
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02060 - Dep. Biosysteme / Dep. of Biosystems Science and Eng.::03807 - Dittrich, Petra / Dittrich, Petra
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02060 - Dep. Biosysteme / Dep. of Biosystems Science and Eng.::03807 - Dittrich, Petra / Dittrich, Petra
en_US
ethz.grant.agreementno
167123
ethz.grant.agreementno
681587
ethz.grant.agreementno
167123
ethz.grant.agreementno
681587
ethz.grant.fundername
SNF
ethz.grant.fundername
EC
ethz.grant.fundername
SNF
ethz.grant.fundername
EC
ethz.grant.funderDoi
10.13039/501100001711
ethz.grant.funderDoi
10.13039/501100000780
ethz.grant.funderDoi
10.13039/501100001711
ethz.grant.funderDoi
10.13039/501100000780
ethz.grant.program
H2020
ethz.grant.program
NFP 72: Gesuch
ethz.grant.program
NFP 72: Gesuch
ethz.grant.program
H2020
ethz.date.deposited
2020-01-14T07:45:15Z
ethz.source
FORM
ethz.eth
yes
en_US
ethz.availability
Metadata only
en_US
ethz.rosetta.installDate
2020-10-21T12:19:34Z
ethz.rosetta.lastUpdated
2022-03-29T03:37:52Z
ethz.rosetta.versionExported
true
ethz.COinS
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Other Conference Item [18110]