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dc.contributor.author
Lähnemann, David
dc.contributor.author
Beerenwinkel, Niko
dc.contributor.author
Jahn, Katharina
dc.contributor.author
et al.
dc.date.accessioned
2020-02-17T09:23:57Z
dc.date.available
2020-02-15T09:23:41Z
dc.date.available
2020-02-17T09:23:57Z
dc.date.issued
2020
dc.identifier.other
10.1186/s13059-020-1926-6
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/399679
dc.identifier.doi
10.3929/ethz-b-000399679
dc.description.abstract
The recent boom in microfluidics and combinatorial indexing strategies, combined with low sequencing costs, has empowered single-cell sequencing technology. Thousands—or even millions—of cells analyzed in a single experiment amount to a data revolution in single-cell biology and pose unique data science problems. Here, we outline eleven challenges that will be central to bringing this emerging field of single-cell data science forward. For each challenge, we highlight motivating research questions, review prior work, and formulate open problems. This compendium is for established researchers, newcomers, and students alike, highlighting interesting and rewarding problems for the coming years.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
BioMed Central
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.title
Eleven grand challenges in single-cell data science
en_US
dc.type
Review Article
dc.rights.license
Creative Commons Attribution 4.0 International
dc.date.published
2020-02-07
ethz.journal.title
Genome Biology
ethz.journal.volume
21
en_US
ethz.journal.issue
1
en_US
ethz.pages.start
31
en_US
ethz.size
35 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
London
en_US
ethz.publication.status
published
en_US
ethz.date.deposited
2020-02-15T09:24:09Z
ethz.source
SCOPUS
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2020-02-17T09:24:09Z
ethz.rosetta.lastUpdated
2020-02-17T09:24:09Z
ethz.rosetta.exportRequired
true
ethz.rosetta.versionExported
true
ethz.COinS
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