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Function and mechanisms in defence strategies
(2022)Current Opinion in Insect ScienceA useful discussion of defence strategies cannot do without linking defence mechanisms to their function, that is, their contributions to fitness. Whereas the former is the domain of immunology, the latter is the subject of evolutionary ecology. For this, the concepts of the defence chart and the disease space can be used to connect the two domains and to sharpen the focus. These use different approaches but converge to the same end, that ...Review Article -
Recent developments in multiscale free energy simulations
(2022)Current Opinion in Structural BiologyPhysics-based free energy simulations enable the rigorous calculation of properties, such as conformational equilibria, solvation or binding free energies. While historically most applications have occurred at the atomistic level of resolution, a range of advances in the past years make it possible now to reliably cross the temporal, spatial and theory scales for the modeling of complex systems or the efficient prediction of results at ...Review Article -
Sieve elements and their cell neighbours in the Arabidopsis root – Roles and relationships
(2022)Journal of Plant PhysiologyReview Article -
Alloy design and adaptation for additive manufacture
(2022)Journal of Materials Processing TechnologyIn this review the authors provide a comprehensive insight into additive manufacturing process mechanics which explore how thermodynamics give rise to characteristic microstructure and property. Discussion is then given over to how solidification microstructure is modified using processing conditions and utilisation of traditional casting methods which give rise to grain refinement and some cases ‘texture by design’. The review then makes ...Review Article -
Reviewing two decades of energy system analysis with bibliometrics
(2022)Renewable and Sustainable Energy ReviewsThe field of Energy System Analysis (ESA) has experienced exponential growth in the number of publications in the last two decades. This paper presents a comprehensive bibliometric analysis on ESA by employing different statistical techniques to investigate the underlying science's structure, characteristics, and patterns. The focus of results is on quantitative indicators relating to the number and type of publication outputs, collaboration ...Review Article -
High-resolution large-scale onshore wind energy assessments: A review of potential definitions, methodologies and future research needs
(2022)Renewable EnergyThe rapid uptake of renewable energy technologies in recent decades has increased the demand of energy researchers, policymakers and energy planners for reliable data on the spatial distribution of their costs and potentials. For onshore wind energy this has resulted in an active research field devoted to analysing these resources for regions, countries or globally. A particular thread of this research attempts to go beyond purely technical ...Review Article -
Conductance-based dynamic causal modeling: A mathematical review of its application to cross-power spectral densities
(2021)NeuroImageDynamic Causal Modeling (DCM) is a Bayesian framework for inferring on hidden (latent) neuronal states, based on measurements of brain activity. Since its introduction in 2003 for functional magnetic resonance imaging data, DCM has been extended to electrophysiological data, and several variants have been developed. Their biophysically motivated formulations make these models promising candidates for providing a mechanistic understanding ...Review Article -
Crossover or non-crossover outcomes: tailored processing of homologous recombination intermediates
(2021)Current opinion in genetics & developmentDNA breaks may arise accidentally in vegetative cells or in a programmed manner in meiosis. The usage of a DNA template makes homologous recombination potentially error-free, however, recombination is not always accurate. Cells possess a remarkable capacity to tailor processing of recombination intermediates to fulfill a particular need. Vegetatively growing cells aim to maintain genome stability and therefore repair accidental breaks ...Review Article -
Experimental analysis and modeling of single-cell time-course data
(2021)Current Opinion in Systems BiologyContemporary single-cell experiments produce vast amounts of data, but the interpretation of these data is far from straightforward. In particular, understanding mechanisms and sources of cell-to-cell variability, given highly complex and nonlinear cellular networks, precludes intuitive interpretation. It requires careful computational and mathematical analysis instead. Here, we discuss different types of single-cell data and computational, ...Review Article -
Membrane-based technologies for per- and poly-fluoroalkyl substances (PFASs) removal from water: Removal mechanisms, applications, challenges and perspectives
(2021)Environment InternationalWater purification from per- and poly-fluoroalkyl substances (PFASs), as a group of persistent and mobile fluoro-organic contaminants, is receiving increasing attention worldwide due to the ubiquitous presence of these highly toxic compounds. To reduce the risk of exposure of human life to PFASs and their dispersion in the environment, various techniques, primarily based on membrane technologies, have been rapidly developed. Here we ...Review Article