A precisely positioned MED12 activation helix stimulates CDK8 kinase activity

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Author
Klatt, Felix
Leitner, Alexander
Kim, Iana V.
Ho-Xuanc, Hung
Schneider, Elisabeth V.
Langhammer, Franziska
Weinmann, Robin
Müller, Melanie R.
Huber, Robert
Meister, Gunter
Kuhn, Claus-D.
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Date
2020-02-11
Type
    Journal Article
Publication status
published
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Journal / series
Proceedings of the National Academy of Sciences of the United States of America
Volume
117(6)
Pages / Article No.
2894 - 2905
Publisher
National Academy of Sciences
Subject
CDK8; MED12; Mediator kinase module; Mediator; kinase inhibitors
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Citations
Cited 32 times in Web of Science
Cited 33 times in Scopus
ETH Bibliography
yes
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