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dc.contributor.author
Thiel, Zacharias
dc.contributor.author
Nguyen, Jade
dc.contributor.author
Rivera Fuentes, Pablo
dc.date.accessioned
2020-05-12T08:46:06Z
dc.date.available
2020-03-13T02:20:39Z
dc.date.available
2020-03-13T09:14:45Z
dc.date.available
2020-05-12T08:46:06Z
dc.date.issued
2020-05-11
dc.identifier.issn
1433-7851
dc.identifier.issn
1521-3773
dc.identifier.issn
0570-0833
dc.identifier.other
10.1002/anie.201915521
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/404712
dc.identifier.doi
10.3929/ethz-b-000404712
dc.description.abstract
Chemical biologists have developed many tools based on genetically encoded macromolecules and small, synthetic compounds. The two different approaches are extremely useful, but they have inherent limitations. In this Minireview, we highlight examples of strategies that combine both concepts to tackle challenging problems in chemical biology. We discuss applications in imaging, with a focus on super‐resolved techniques, and in probe and drug delivery. We propose future directions in this field, hoping to inspire chemical biologists to develop new combinations of synthetic and genetically encoded probes.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
Wiley
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject
Bioorthogonal labeling
en_US
dc.subject
Biosensors
en_US
dc.subject
Drug delivery
en_US
dc.subject
Fluorescent probes
en_US
dc.subject
Genetically encoded tags
en_US
dc.title
Genetically Encoded Activators of Small Molecules for Imaging and Drug Delivery
en_US
dc.type
Review Article
dc.rights.license
Creative Commons Attribution 4.0 International
dc.date.published
2020-01-02
ethz.journal.title
Angewandte Chemie. International Edition
ethz.journal.volume
59
en_US
ethz.journal.issue
20
en_US
ethz.journal.abbreviated
Angew. Chem. Int. Ed.
ethz.pages.start
7669
en_US
ethz.pages.end
7677
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.grant
Development of Intracellular Photoactivatable Probes
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
Weinheim
en_US
ethz.publication.status
published
en_US
ethz.grant.agreementno
165551
ethz.grant.fundername
SNF
ethz.grant.funderDoi
10.13039/501100001711
ethz.grant.program
Projektförderung in Mathematik, Natur- und Ingenieurwissenschaften (Abteilung II)
ethz.date.deposited
2020-03-13T02:20:53Z
ethz.source
WOS
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2020-05-12T08:46:17Z
ethz.rosetta.lastUpdated
2021-02-15T10:58:16Z
ethz.rosetta.versionExported
true
ethz.COinS
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