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dc.contributor.author
Bauch, Angela
dc.contributor.author
Adamczyk, Izabela
dc.contributor.author
Buczek, Piotr
dc.contributor.author
Elmer, Franz-Josef
dc.contributor.author
Enimanev, Kaloyan
dc.contributor.author
Kohler, Manuel
dc.contributor.author
Pylak, Tomasz
dc.contributor.author
Quandt, Andreas
dc.contributor.author
Ramakrishnan, Chandrasekhar
dc.contributor.author
Beisel, Christian
dc.contributor.author
Malmström, Lars
dc.contributor.author
Aebersold, Ruedi
dc.contributor.author
Rinn, Bernd
dc.date.accessioned
2018-09-03T11:16:31Z
dc.date.available
2017-06-09T17:22:39Z
dc.date.available
2018-09-03T11:16:31Z
dc.date.issued
2011-12
dc.identifier.issn
1471-2105
dc.identifier.other
10.1186/1471-2105-12-468
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/41687
dc.identifier.doi
10.3929/ethz-b-000041687
dc.description.abstract
Background Modern data generation techniques used in distributed systems biology research projects often create datasets of enormous size and diversity. We argue that in order to overcome the challenge of managing those large quantitative datasets and maximise the biological information extracted from them, a sound information system is required. Ease of integration with data analysis pipelines and other computational tools is a key requirement for it. Results We have developed openBIS, an open source software framework for constructing user-friendly, scalable and powerful information systems for data and metadata acquired in biological experiments. openBIS enables users to collect, integrate, share, publish data and to connect to data processing pipelines. This framework can be extended and has been customized for different data types acquired by a range of technologies. Conclusions openBIS is currently being used by several SystemsX.ch and EU projects applying mass spectrometric measurements of metabolites and proteins, High Content Screening, or Next Generation Sequencing technologies. The attributes that make it interesting to a large research community involved in systems biology projects include versatility, simplicity in deployment, scalability to very large data, flexibility to handle any biological data type and extensibility to the needs of any research domain.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
BioMed Central
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/2.0/
dc.subject
File System
en_US
dc.subject
Data Space
en_US
dc.subject
Application Server
en_US
dc.subject
Bulk Data
en_US
dc.subject
Metadata File
en_US
dc.title
openBIS: a flexible framework for managing and analyzing complex data in biology research
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 2.0 Generic
ethz.journal.title
BMC Bioinformatics
ethz.journal.volume
12
en_US
ethz.pages.start
468
en_US
ethz.size
19 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.wos
ethz.publication.place
London
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
02277 - Center for Information Sciences and Databases (C-ISD) / Center for Information Sciences and Databases (C-ISD)
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02030 - Dep. Biologie / Dep. of Biology::02538 - Institut für Molekulare Systembiologie / Institute for Molecular Systems Biology::03663 - Aebersold, Rudolf (emeritus) / Aebersold, Rudolf (emeritus)
en_US
ethz.leitzahl.certified
02277 - Center for Information Sciences and Databases (C-ISD) / Center for Information Sciences and Databases (C-ISD)
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02030 - Dep. Biologie / Dep. of Biology::02538 - Institut für Molekulare Systembiologie / Institute for Molecular Systems Biology::03663 - Aebersold, Rudolf (emeritus) / Aebersold, Rudolf (emeritus)
ethz.date.deposited
2017-06-09T17:22:45Z
ethz.source
ECIT
ethz.identifier.importid
imp59364eabd78ca26980
ethz.ecitpid
pub:69627
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2017-07-15T08:02:28Z
ethz.rosetta.lastUpdated
2019-01-02T13:42:51Z
ethz.rosetta.exportRequired
true
ethz.rosetta.versionExported
true
ethz.COinS
ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.atitle=openBIS:%20a%20flexible%20framework%20for%20managing%20and%20analyzing%20complex%20data%20in%20biology%20research&rft.jtitle=BMC%20Bioinformatics&rft.date=2011-12&rft.volume=12&rft.spage=468&rft.issn=1471-2105&rft.au=Bauch,%20Angela&Adamczyk,%20Izabela&Buczek,%20Piotr&Elmer,%20Franz-Josef&Enimanev,%20Kaloyan&rft.genre=article&rft_id=info:doi/10.1186/1471-2105-12-468&
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