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dc.contributor.author
Dennis, Alice B.
dc.contributor.author
Vorburger, Christoph
dc.contributor.author
et al.
dc.date.accessioned
2020-06-10T15:53:06Z
dc.date.available
2020-06-06T02:35:37Z
dc.date.available
2020-06-10T15:53:06Z
dc.date.issued
2020
dc.identifier.other
10.1186/s12864-020-6764-0
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/418643
dc.identifier.doi
10.3929/ethz-b-000418643
dc.description.abstract
Background Parasitoid wasps have fascinating life cycles and play an important role in trophic networks, yet little is known about their genome content and function. Parasitoids that infect aphids are an important group with the potential for biological control. Their success depends on adapting to develop inside aphids and overcoming both host aphid defenses and their protective endosymbionts. Results We present the de novo genome assemblies, detailed annotation, and comparative analysis of two closely related parasitoid wasps that target pest aphids: Aphidius ervi and Lysiphlebus fabarum (Hymenoptera: Braconidae: Aphidiinae). The genomes are small (139 and 141 Mbp) and the most AT-rich reported thus far for any arthropod (GC content: 25.8 and 23.8%). This nucleotide bias is accompanied by skewed codon usage and is stronger in genes with adult-biased expression. AT-richness may be the consequence of reduced genome size, a near absence of DNA methylation, and energy efficiency. We identify missing desaturase genes, whose absence may underlie mimicry in the cuticular hydrocarbon profile of L. fabarum. We highlight key gene groups including those underlying venom composition, chemosensory perception, and sex determination, as well as potential losses in immune pathway genes. Conclusions These findings are of fundamental interest for insect evolution and biological control applications. They provide a strong foundation for further functional studies into coevolution between parasitoids and their hosts. Both genomes are available at https://bipaa.genouest.org.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
BioMed Central
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject
Parasitoid wasp
en_US
dc.subject
Aphid host
en_US
dc.subject
Aphidius ervi
en_US
dc.subject
Lysiphlebus fabarum
en_US
dc.subject
GC content
en_US
dc.subject
de novo genome assembly
en_US
dc.subject
DNA methylation loss
en_US
dc.subject
Chemosensory gene
en_US
dc.subject
Venom proteins
en_US
dc.subject
Toll and Imd pathways
en_US
dc.title
Functional insights from the GC-poor genomes of two aphid parasitoids, Aphidius ervi and Lysiphlebus fabarum
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 4.0 International
dc.date.published
2020-05-29
ethz.journal.title
BMC Genomics
ethz.journal.volume
21
en_US
ethz.journal.issue
1
en_US
ethz.pages.start
376
en_US
ethz.size
27 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.grant
Symbiont-mediated coevolution in an insect host-parasitoid system
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
London
en_US
ethz.publication.status
published
en_US
ethz.grant.agreementno
146341
ethz.grant.fundername
SNF
ethz.grant.funderDoi
10.13039/501100001711
ethz.grant.program
SNF-Förderungsprofessuren: Fortsetzungsgesuche
ethz.date.deposited
2020-06-06T02:35:59Z
ethz.source
SCOPUS
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2020-06-10T15:53:18Z
ethz.rosetta.lastUpdated
2021-02-15T14:31:31Z
ethz.rosetta.versionExported
true
ethz.COinS
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