Halogen Bonding at the Active Sites of Human Cathepsin L and MEK1 Kinase: Efficient Interactions in Different Environments

Hardegger, Leo A.; Kuhn, Bernd; Spinnler, Beat; Anselm, Lilli; Ecabert, Robert; Stihle, Martine; Gsell, Bernard; Thoma, Ralf; Diez, Joachim; Benz, Jörg; Plancher, Jean-Marc; Hartmann, Guido; Isshiki, Yoshiaki; Morikami, Kenji; Shimma, Nobuo; Haap, Wolfgang; Banner, David W.; Diederich, François

doi:10.1002/cmdc.201100353

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Author

Date

2011-11

Type

Journal Article

Citations

Cited 94 times in Web of Science

ETH Bibliography

yes

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Publication status

published

External links

https://doi.org/10.1002/cmdc.201100353

Journal / series

ChemMedChem

Volume

6(11)

Pages / Article No.

2048 - 2054

Publisher

Wiley

Subject

Halogen bonding; Medicinal chemistry; Molecular recognition; Protein-ligand interactions; Structure-activity relationship

Organisational unit

03344 - Diederich, François (emeritus)

Notes

Received 19 July 2011, Published online 06 September 2011.

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Citations

Cited 94 times in Web of Science

ETH Bibliography

yes

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Halogen Bonding at the Active Sites of Human Cathepsin L and MEK1 Kinase