Synthetische Hydrogele als 3D-Matrix für definierte Gewebemodelle

Abstract

Hydrogels are water-swollen polymer networks that are widely used as scaffold materials in 3D cell biology and tissue engineering. Biologists have commonly used hydrogels generated from natural extracellular matrix (ECM) polymers, which present challenges for biomedical applications due to their natural origin. Synthetic hydrogels are fabricated with fully defi ned material properties and can be modifi ed to mimic the ECM. In this article, we discuss the design, recent applications and power of synthetic hydrogels for 3D tissue models. (© 2020 Springer).