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dc.contributor.author
Dominguez-Bello, Maria G.
dc.contributor.author
De Jesus-Laboy, Kassandra M.
dc.contributor.author
Shen, Nan
dc.contributor.author
Cox, Laura M.
dc.contributor.author
Amir, Amnon
dc.contributor.author
Gonzalez, Antonio
dc.contributor.author
Bokulich, Nicholas
dc.contributor.author
Song, Se Jin
dc.contributor.author
Hoashi, Marina
dc.contributor.author
Rivera-Vinas, Juana I.
dc.contributor.author
Mendez, Keimari
dc.contributor.author
Knight, Rob
dc.contributor.author
Clemente, Jose C.
dc.date.accessioned
2020-08-17T10:59:29Z
dc.date.available
2020-08-12T10:13:01Z
dc.date.available
2020-08-17T10:59:29Z
dc.date.issued
2016-03
dc.identifier.issn
1078-8956
dc.identifier.issn
1546-170X
dc.identifier.other
10.1038/nm.4039
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/431191
dc.description.abstract
Exposure of newborns to the maternal vaginal microbiota is interrupted with cesarean birthing. Babies delivered by cesarean section (C-section) acquire a microbiota that differs from that of vaginally delivered infants, and C-section delivery has been associated with increased risk for immune and metabolic disorders. Here we conducted a pilot study in which infants delivered by C-section were exposed to maternal vaginal fluids at birth. Similarly to vaginally delivered babies, the gut, oral and skin bacterial communities of these newborns during the first 30 d of life was enriched in vaginal bacteria - which were underrepresented in unexposed C-section-delivered infants - and the microbiome similarity to those of vaginally delivered infants was greater in oral and skin samples than in anal samples. Although the long-term health consequences of restoring the microbiota of C-section-delivered infants remain unclear, our results demonstrate that vaginal microbes can be partially restored at birth in C-section-delivered babies. © 2016 Nature America, Inc.
en_US
dc.language.iso
en
en_US
dc.publisher
Nature Publishing Group
en_US
dc.title
Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer
en_US
dc.type
Journal Article
dc.date.published
2016-02-01
ethz.journal.title
Nature Medicine
ethz.journal.volume
22
en_US
ethz.journal.issue
3
en_US
ethz.journal.abbreviated
Nat Med
ethz.pages.start
250
en_US
ethz.publication.place
London
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02070 - Dep. Gesundheitswiss. und Technologie / Dep. of Health Sciences and Technology::02701 - Inst.f. Lebensmittelwiss.,Ernährung,Ges. / Institute of Food, Nutrition, and Health::09714 - Bokulich, Nicholas / Bokulich, Nicholas
en_US
ethz.date.deposited
2020-08-12T10:13:09Z
ethz.source
BATCH
ethz.eth
no
en_US
ethz.availability
Metadata only
en_US
ethz.rosetta.installDate
2020-08-17T10:59:41Z
ethz.rosetta.lastUpdated
2021-02-15T16:11:29Z
ethz.rosetta.exportRequired
true
ethz.rosetta.versionExported
true
ethz.COinS
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