Metadata only
Date
2020Type
- Journal Article
Abstract
Food has a major impact on all aspects of health. Recent data suggest that food composition can also affect susceptibility to infections by enteropathogenic bacteria. Here, we discuss how food may alter the microbiota as well as mucosal defenses and how this can affect infection. Salmonella Typhimurium diarrhea serves as a paradigm, and complementary evidence comes from other pathogens. We discuss the effects of food composition on colonization resistance, host defenses, and the infection process as well as the merits and limitations of mouse models and experimental foods, which are available to decipher the underlying mechanisms. Show more
Publication status
publishedExternal links
Journal / series
Annual Review of MicrobiologyVolume
Pages / Article No.
Publisher
Annual ReviewsSubject
Enterobacteriaceae; Salmonella Typhimurium; gut microbiota; mouse model; diet; diseaseOrganisational unit
03589 - Hardt, Wolf-Dietrich / Hardt, Wolf-Dietrich
Funding
173338 - Deciphering the initial steps that lead to Salmonella Typhimurium diarrhea (SNF)
192567 - Mechanisms controlling the Salmonella Typhimurium gut infection (SNF)
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