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dc.contributor.author
Lunha, Kamonwan
dc.contributor.author
Leangapichart, Thongpan
dc.contributor.author
Jiwakanon, Jatesada
dc.contributor.author
Angkititrakul, Sunpetch
dc.contributor.author
Sunde, Marianne
dc.contributor.author
Järhult, Josef D.
dc.contributor.author
Ström Hallenberg, Gunilla
dc.contributor.author
Hickman, Rachel A.
dc.contributor.author
Van Boeckel, Thomas
dc.contributor.author
Magnusson, Ulf
dc.date.accessioned
2020-10-09T10:54:13Z
dc.date.available
2020-10-09T03:05:34Z
dc.date.available
2020-10-09T10:54:13Z
dc.date.issued
2020-09-30
dc.identifier.issn
2079-6382
dc.identifier.other
10.3390/antibiotics9100662
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/445185
dc.identifier.doi
10.3929/ethz-b-000445185
dc.description.abstract
The overall aim of the current study was to test the hypotheses that (i) antibiotic resistance in bacteria were more frequent in clinically health pigs in intensified company owned, medium-scale farms (MSFs) (100–500 sows) than in pigs in family-owned, small-scale farms (SSFs) (1–50 sows) and (ii) that farmers working at the MSFs were more prone to attain antibiotic resistant bacteria than farmers working at SSFs. The study was conducted in North-Eastern Thailand, comprising fecal Escherichia coli isolates from pigs, farmers working with the pigs (contact humans) and persons living in the same household as the farmer (non-contact humans) at 51 MSFs and 113 SSFs. Samples from all farms were also screened for methicillin-resistant staphylococcus aureus (MRSA), which was not detected in pig samples, but was found in one human sample. Susceptibility was tested by disc-diffusion for seven antibiotics commonly used in the study area. Resistance in pig isolates from MSFs were more frequent for chloramphenicol which (P < 0.001), trimethoprim/sulfamethoxazole (P < 0.001) and gentamicin (P < 0.05) compared with isolates from SSFs, whereas the opposite was true for tetracycline (P < 0.01). Resistance in the human isolates was lower than those in the isolates from pigs for tetracycline, trimethoprim/sulfamethoxazole and chloramphenicol (P < 0.001). The frequency of resistance in the contact human samples from SSFs and MSFs did not differ. There was no difference between isolates from contact and non-contact humans for any of the tested antibiotics. Multidrug resistance in isolates from pigs was 26%, significantly higher (P < 0.01) than the 13% from humans. The data indicate that (i) resistance to antibiotics, including those critical and highly important for human medicine, were more common in fecal E. coli from pigs at the MSFs than at the SSFs, whereas (ii) the resistance in fecal E. coli from pig farmers seemed not to be influenced by the level of intensification of the farm they were working at. © 2020 by the authors. Licensee MDPI, Basel, Switzerland.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
MDPI
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.title
Antimicrobial resistance in fecal escherichia coli from humans and pigs at farms at different levels of intensification
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 4.0 International
ethz.journal.title
Antibiotics
ethz.journal.volume
9
en_US
ethz.journal.issue
10
en_US
ethz.pages.start
662
en_US
ethz.size
11 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
Basel
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02350 - Dep. Umweltsystemwissenschaften / Dep. of Environmental Systems Science::02723 - Institut für Umweltentscheidungen / Institute for Environmental Decisions::09673 - Van Boeckel, Thomas (ehemalig) / Van Boeckel, Thomas (former)
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02350 - Dep. Umweltsystemwissenschaften / Dep. of Environmental Systems Science::02723 - Institut für Umweltentscheidungen / Institute for Environmental Decisions::09673 - Van Boeckel, Thomas (ehemalig) / Van Boeckel, Thomas (former)
ethz.date.deposited
2020-10-09T03:05:41Z
ethz.source
SCOPUS
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2020-10-09T10:54:30Z
ethz.rosetta.lastUpdated
2023-02-06T20:31:14Z
ethz.rosetta.versionExported
true
ethz.COinS
ctx_ver=Z39.88-2004&amp;rft_val_fmt=info:ofi/fmt:kev:mtx:journal&amp;rft.atitle=Antimicrobial%20resistance%20in%20fecal%20escherichia%20coli%20from%20humans%20and%20pigs%20at%20farms%20at%20different%20levels%20of%20intensification&amp;rft.jtitle=Antibiotics&amp;rft.date=2020-09-30&amp;rft.volume=9&amp;rft.issue=10&amp;rft.spage=662&amp;rft.issn=2079-6382&amp;rft.au=Lunha,%20Kamonwan&amp;Leangapichart,%20Thongpan&amp;Jiwakanon,%20Jatesada&amp;Angkititrakul,%20Sunpetch&amp;Sunde,%20Marianne&amp;rft.genre=article&amp;rft_id=info:doi/10.3390/antibiotics9100662&amp;
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