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dc.contributor.author
Brassil, Bridget
dc.contributor.author
Roese Mores, Carine
dc.contributor.author
Wolfe, Alan J.
dc.contributor.author
Putonti, Catherine
dc.date.accessioned
2020-11-19T09:10:49Z
dc.date.available
2020-11-18T15:08:14Z
dc.date.available
2020-11-19T09:10:49Z
dc.date.issued
2020
dc.identifier.issn
0022-1317
dc.identifier.issn
1465-2099
dc.identifier.other
10.1099/jgv.0.001407
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/451912
dc.identifier.doi
10.3929/ethz-b-000451912
dc.description.abstract
Streptococcus anginosus is an often overlooked and understudied emerging pathogen inhabiting many areas of the human body. Through our sequencing of S. anginosus strains isolated from the female bladder microbiota, we detected numerous prophage sequences. Bioinformatic analysis of these sequences identified 17 distinct groups of S. anginosus prophages. The majority of these phages exhibit no sequence homology to previously characterized temperate or virulent phage sequences, indicating an unexplored diversity of Streptococcus phages. By culturing these bacterial isolates, we confirmed that the prophages of five of these groups are capable of induction. One of these putative phages was imaged, the first such evidence of an S . anginosus virus-like particle; it exhibits morphological characteristics of siphoviruses.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
Microbiology Society
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject
Streptococcus anginosus
en_US
dc.subject
Bacteriophage
en_US
dc.subject
Urinary tract
en_US
dc.title
Characterization and spontaneous induction of urinary tract Streptococcus anginosus prophages
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 4.0 International
dc.date.published
2020-04-21
ethz.journal.title
Journal of General Virology
ethz.journal.volume
101
en_US
ethz.journal.issue
6
en_US
ethz.journal.abbreviated
J. gen. virol.
ethz.pages.start
685
en_US
ethz.pages.end
691
en_US
ethz.size
7 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.publication.place
Monroe, NJ
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02030 - Dep. Biologie / Dep. of Biology::02520 - Institut für Mikrobiologie / Institute of Microbiology
en_US
ethz.date.deposited
2020-11-18T15:08:24Z
ethz.source
FORM
ethz.eth
no
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2020-11-19T09:11:03Z
ethz.rosetta.lastUpdated
2021-02-15T20:50:15Z
ethz.rosetta.versionExported
true
ethz.COinS
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