- Review Article
Rights / licenseCreative Commons Attribution 4.0 International
Extracellular vesicles (EVs) are biocompatible, nano‐sized secreted vesicles containing many types of biomolecules, including proteins, RNAs, DNAs, lipids, and metabolites. Their low immunogenicity and ability to functionally modify recipient cells by transferring diverse bioactive constituents make them an excellent candidate for a next‐generation drug delivery system. Here, the recent advances in EV biology and emerging strategies of EV bioengineering are summarized, and the prospects for clinical translation of bioengineered EVs and the challenges to be overcome are discussed. © 2020 The Authors. Published by Wiley‐VCH GmbH. Show more
Journal / seriesAdvanced Science
Pages / Article No.
SubjectBioengineering; Delivery systems; Exosomes; Extracellular vesicles; Microvesicles
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