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dc.contributor.author
Teng, Fei
dc.contributor.author
Fussenegger, Martin
dc.date.accessioned
2021-03-02T06:51:14Z
dc.date.available
2020-12-10T04:00:49Z
dc.date.available
2020-12-21T13:05:41Z
dc.date.available
2021-03-02T06:51:14Z
dc.date.issued
2021-01-06
dc.identifier.issn
2198-3844
dc.identifier.other
10.1002/advs.202003505
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/455604
dc.identifier.doi
10.3929/ethz-b-000455604
dc.description.abstract
Extracellular vesicles (EVs) are biocompatible, nano‐sized secreted vesicles containing many types of biomolecules, including proteins, RNAs, DNAs, lipids, and metabolites. Their low immunogenicity and ability to functionally modify recipient cells by transferring diverse bioactive constituents make them an excellent candidate for a next‐generation drug delivery system. Here, the recent advances in EV biology and emerging strategies of EV bioengineering are summarized, and the prospects for clinical translation of bioengineered EVs and the challenges to be overcome are discussed. © 2020 The Authors. Published by Wiley‐VCH GmbH.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
Wiley
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject
Bioengineering
en_US
dc.subject
Delivery systems
en_US
dc.subject
Exosomes
en_US
dc.subject
Extracellular vesicles
en_US
dc.subject
Microvesicles
en_US
dc.title
Shedding Light on Extracellular Vesicle Biogenesis and Bioengineering
en_US
dc.type
Review Article
dc.rights.license
Creative Commons Attribution 4.0 International
dc.date.published
2020-11-27
ethz.journal.title
Advanced Science
ethz.journal.volume
8
en_US
ethz.journal.issue
1
en_US
ethz.journal.abbreviated
Adv. Sci.
ethz.pages.start
2003505
en_US
ethz.size
17 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.grant
Electrogenetics - Shaping Electrogenetic Interfaces for Closed-Loop Voltage-Controlled Gene Expression
en_US
ethz.identifier.wos
ethz.publication.place
Weinheim
en_US
ethz.publication.status
published
en_US
ethz.grant.agreementno
785800
ethz.grant.fundername
EC
ethz.grant.funderDoi
10.13039/501100000780
ethz.grant.program
H2020
ethz.date.deposited
2020-12-10T04:00:55Z
ethz.source
WOS
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2021-03-02T06:51:23Z
ethz.rosetta.lastUpdated
2021-03-02T06:51:23Z
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true
ethz.rosetta.versionExported
true
ethz.COinS
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