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dc.contributor.author
Duverney, Cedric
dc.contributor.author
Abbasi, Hamed
dc.contributor.author
Berkelaar, Majoska H.M.
dc.contributor.author
Pelttari, Karoliina
dc.contributor.author
Cattin, Philippe C.
dc.contributor.author
Barbero, Andrea
dc.contributor.author
Zam, Azhar
dc.contributor.author
Rauter, Georg
dc.date.accessioned
2021-01-11T10:59:17Z
dc.date.available
2020-12-16T14:22:35Z
dc.date.available
2021-01-04T12:15:46Z
dc.date.available
2021-01-11T10:59:17Z
dc.date.issued
2021-03
dc.identifier.issn
1932-6181
dc.identifier.issn
1932-619X
dc.identifier.other
10.1115/1.4049396
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/456706
dc.description.abstract
Preparation of biological samples for further processing or analysis is generally performed manually by means of standard mechanical tools such as scalpels or biopsy punches. While this approach is uncomplicated and swift, it entails constraints such as low, operator-dependent cutting accuracy and reproducibility. Tissue segments surrounding the cut may further suffer mechanical and thermal damage due to shear forces and friction between tool and sample. These hindrances affect procedures both in the laboratory environment as well as within clinical settings. A system has been developed leveraging robotic positioning and laser light for precise, controlled, and contactless tissue ablation, and providing a concise and intuitive graphical user interface. Additionally, sterility of the process is demonstrated, a paramount element for clinical application. The proposed process does not require sterilization of the robotic components or the lasers, easing a prospective integration into existing workflows. In the context of the current work, mainly cartilage repair surgery is targeted. The proposed system allows for highly accurate and reproducible shaping of the cartilage lesion area as well as its corresponding engineered cartilage graft, possibly leading to better and faster integration at the defect site. Promising results could be obtained in a first test series with human cartilage samples, validating functionality of the preparation system and feasibility of the sterility concept.
en_US
dc.language.iso
en
en_US
dc.publisher
American Society of Mechanical Engineers
en_US
dc.title
Sterile Tissue Ablation Using Laser Light - System Design, Experimental Validation, and Outlook on Clinical Applicability
en_US
dc.type
Journal Article
dc.date.published
2020-12-21
ethz.journal.title
Journal of Medical Devices
ethz.journal.volume
15
en_US
ethz.journal.issue
1
en_US
ethz.journal.abbreviated
J. Med. Devices
ethz.pages.start
011104
en_US
ethz.size
12 p.
en_US
ethz.publication.place
New York, NY
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02070 - Dep. Gesundheitswiss. und Technologie / Dep. of Health Sciences and Technology::03654 - Riener, Robert / Riener, Robert
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02070 - Dep. Gesundheitswiss. und Technologie / Dep. of Health Sciences and Technology::03654 - Riener, Robert / Riener, Robert
en_US
ethz.date.deposited
2020-12-16T14:22:45Z
ethz.source
FORM
ethz.eth
no
en_US
ethz.availability
Metadata only
en_US
ethz.rosetta.installDate
2021-01-11T10:59:26Z
ethz.rosetta.lastUpdated
2022-03-29T04:46:35Z
ethz.rosetta.versionExported
true
ethz.COinS
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