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dc.contributor.author
Kocic, Jovana
dc.contributor.author
Günther, Detlef
dc.contributor.author
Hattendorf, Bodo
dc.date.accessioned
2021-03-25T08:20:22Z
dc.date.available
2020-12-18T09:40:11Z
dc.date.available
2020-12-21T13:00:05Z
dc.date.available
2020-12-22T14:23:21Z
dc.date.available
2020-12-22T14:35:32Z
dc.date.available
2021-01-14T09:34:45Z
dc.date.available
2021-03-25T08:20:22Z
dc.date.issued
2021-01
dc.identifier.issn
0267-9477
dc.identifier.issn
1364-5544
dc.identifier.other
10.1039/d0ja00421a
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/457077
dc.identifier.doi
10.3929/ethz-b-000457077
dc.description.abstract
Single particle inductively coupled plasma mass spectrometry (sp-ICPMS) is an attractive technique for fast measurement of elemental composition, mass and particle number concentration (PNC) of metal containing nanoparticles (NPs). In order to investigate NPs <10 nm using ICPMS, low instrumental background and high detection efficiency are primary requirements. This study evaluated the performance of a sector-field ICPMS with standard and enhanced sensitivity (“Jet”) vacuum interfaces with different sample introduction setups: conventional pneumatic nebulization with (DSN) and without aerosol desolvation (PN) and microdroplet generation (MDG). Additionally, the influence of nitrogen gas as an addition to a dry aerosol was studied. In this study, transport efficiencies (TEs) and detection efficiencies (DEs) are determined for the different instrumental setups. Gold NP suspensions were analysed and evaluated for PNC and size. Applying counting statistics, the size limit of detection (LODsize) of gold nanoparticles (Au NPs) was estimated to be 6.1 nm and 4.7 nm for PN and MDG with the standard interface, and 3.6 nm and 3.1 nm for DSN and MDG with the “Jet” interface and nitrogen addition, respectively. Additionally, DEs for various elements were determined. 11 isotopes (27Al, 47Ti, 63Cu, 107Ag, 111Cd, 115In, 133Cs, 140Ce, 193Ir, 197Au, and 238U) were measured at a mass resolving power (MRP) of 300 while an MRP of 4000 was used for 56Fe and 66Zn. DEs obtained for the conventional nebulization system with a spray chamber (PN) were in the range of 10−4 to 10−2 counts per atom (low resolution) and 10−6 to 10−5 counts per atom (medium resolution), while significant improvement in DE was obtained for the MDG setup with the “Jet” interface and nitrogen addition resulting in the range of 10−2 to 10−1 counts per atom (low resolution) and 10−4 to 10−3 counts per atom (medium resolution). The enhancement in DE was most pronounced for isotopes of lower m/z indicating reduced mass discrimination of the “Jet” interface with nitrogen gas added to the sample aerosol. The corresponding LODSIZE could thus be decreased by 10 or 2 times for example for Al- and Au-containing NPs, respectively. At the same time the use of an MDG for sample introduction allowed for 98.5% TE in the analyses of NP suspensions, while a TE of 10% (PN) or 23% (DSN) was obtained with pneumatic nebulizers.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
Royal Society of Chemistry
en_US
dc.rights.uri
http://creativecommons.org/licenses/by-nc/3.0/
dc.title
Improving detection capability for single particle inductively coupled plasma mass spectrometry with microdroplet sample introduction
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution-NonCommercial 3.0 Unported
dc.date.published
2020-11-26
ethz.journal.title
Journal of Analytical Atomic Spectrometry
ethz.journal.volume
36
en_US
ethz.journal.issue
1
en_US
ethz.journal.abbreviated
J Anal At Spectrom
ethz.pages.start
233
en_US
ethz.pages.end
242
en_US
ethz.size
10 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
Cambridge
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02020 - Dep. Chemie und Angewandte Biowiss. / Dep. of Chemistry and Applied Biosc.::02513 - Laboratorium für Anorganische Chemie / Laboratory of Inorganic Chemistry::03512 - Günther, Detlef / Günther, Detlef
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02020 - Dep. Chemie und Angewandte Biowiss. / Dep. of Chemistry and Applied Biosc.::02513 - Laboratorium für Anorganische Chemie / Laboratory of Inorganic Chemistry::03512 - Günther, Detlef / Günther, Detlef
en_US
ethz.date.deposited
2020-12-18T09:40:18Z
ethz.source
FORM
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2021-03-25T08:20:36Z
ethz.rosetta.lastUpdated
2023-02-06T21:38:22Z
ethz.rosetta.versionExported
true
ethz.COinS
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