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dc.contributor.author
van der Wejiden, Vera A.
dc.contributor.author
Rüegg, Anna B.
dc.contributor.author
Bernal-Uloa, Sandra M.
dc.contributor.author
Ulbrich, Susanne E.
dc.date.accessioned
2021-01-22T07:53:11Z
dc.date.available
2021-01-20T12:22:46Z
dc.date.available
2021-01-22T07:53:11Z
dc.date.issued
2021-01-08
dc.identifier.issn
1031-3613
dc.identifier.other
10.1071/RD20256
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/464012
dc.description.abstract
In species displaying embryonic diapause, the developmental pace of the embryo is either temporarily and reversibly halted or largely reduced. Only limited knowledge on its regulation and the inhibition of cell proliferation extending pluripotency is available. In contrast with embryos from other diapausing species that reversibly halt during diapause, embryos of the roe deer Capreolus capreolus slowly proliferate over a period of 4-5 months to reach a diameter of approximately 4 mm before elongation. The diapausing roe deer embryos present an interesting model species for research on preimplantation developmental progression. Based on our and other research, we summarise the available knowledge and indicate that the use of embryonic stem cells (ESCs) would help to increase our understanding of embryonic diapause. We report on known molecular mechanisms regulating embryonic diapause, as well as cellular dormancy of pluripotent cells. Further, we address the promising application of ESCs to study embryonic diapause, and highlight the current knowledge on the cellular microenvironment regulating embryonic diapause and cellular dormancy. © 2021 Journal Compilation
en_US
dc.language.iso
en
en_US
dc.publisher
CSIRO
en_US
dc.subject
dormancy
en_US
dc.subject
embryonic diapause
en_US
dc.subject
embryonic stem cells
en_US
dc.subject
European roe deer Capreolus capreolus
en_US
dc.title
Embryonic diapause in mammals and dormancy in embryonic stem cells with the European roe deer as experimental model
en_US
dc.type
Journal Article
ethz.journal.title
Reproduction, Fertility and Development
ethz.journal.volume
33
en_US
ethz.journal.issue
2
en_US
ethz.journal.abbreviated
Reprod. fertil. dev.
ethz.pages.start
76
en_US
ethz.pages.end
81
en_US
ethz.size
6 p.
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
Collingwood
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02350 - Dep. Umweltsystemwissenschaften / Dep. of Environmental Systems Science::02703 - Institut für Agrarwissenschaften / Institute of Agricultural Sciences::03999 - Ulbrich, Susanne / Ulbrich, Susanne
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02350 - Dep. Umweltsystemwissenschaften / Dep. of Environmental Systems Science::02703 - Institut für Agrarwissenschaften / Institute of Agricultural Sciences::03999 - Ulbrich, Susanne / Ulbrich, Susanne
ethz.date.deposited
2021-01-20T12:22:55Z
ethz.source
SCOPUS
ethz.eth
yes
en_US
ethz.availability
Metadata only
en_US
ethz.rosetta.installDate
2021-01-22T07:53:20Z
ethz.rosetta.lastUpdated
2021-01-22T07:53:20Z
ethz.rosetta.exportRequired
true
ethz.rosetta.versionExported
true
ethz.COinS
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