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dc.contributor.author
Gao, Hanchao
dc.contributor.author
Hammer, Tobias
dc.contributor.author
Zhang, Xiaole
dc.contributor.author
He, Weidong
dc.contributor.author
Xu, Guangbiao
dc.contributor.author
Wang, Jing
dc.date.accessioned
2021-01-22T09:02:18Z
dc.date.available
2021-01-22T03:49:41Z
dc.date.available
2021-01-22T09:02:18Z
dc.date.issued
2021-01
dc.identifier.issn
2452-0748
dc.identifier.other
10.1016/j.impact.2021.100292
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/464571
dc.description.abstract
The booming development of commercial products containing graphene nanoplatelets (GNPs) triggers growing concerns over their release into the air. Precise prediction of human respiratory system deposition of airborne GNPs, especially in alveolar region, is very important for inhalation exposure assessment. In this study, the pulmonary deposition of airborne GNPs was predicted by the multiple-path particle dosimetry (MPPD) model with consideration of GNPs plate-like shape and folded structure effect. Different equivalent diameters of GNPs were derived and utilized to describe different deposition mechanisms in the MPPD model. Both of small GNPs (geometric lateral size dg < 0.1 μm) and large GNPs (dg > 10 μm) had high deposition fractions in human respiratory system. The total deposition fractions for 0.1 and 30 μm GNPs were 41.6% and 75.6%, respectively. Most of the small GNPs deposited in the alveolar region, while the large GNPs deposited in the head airways. The aerodynamic diameter of GNPs was much smaller than the geometric lateral dimension due to the nanoscale thickness. For GNPs with geometric lateral size of 30 μm, the aerodynamic diameter was 2.98 μm. The small aerodynamic diameter of plate-like GNPs enabled deposition in the alveolar region, and folded GNPs had higher alveolar deposition than planar GNPs. Heavy breathing led to higher GNPs deposition fraction in head airways and lower deposition fractions in the alveolar region than resting breathing.
en_US
dc.language.iso
en
en_US
dc.publisher
Elsevier
en_US
dc.subject
Graphene nanoplatelets
en_US
dc.subject
Aerodynamic diameter
en_US
dc.subject
Lung deposition
en_US
dc.subject
Multiple-path particle dosimetry model
en_US
dc.subject
Exposure assessment
en_US
dc.title
Quantifying respiratory tract deposition of airborne graphene nanoplatelets: The impact of plate-like shape and folded structure
en_US
dc.type
Journal Article
dc.date.published
2021-01-10
ethz.journal.title
NanoImpact
ethz.journal.volume
21
en_US
ethz.pages.start
100292
en_US
ethz.size
13 p.
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
Amsterdam
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02115 - Dep. Bau, Umwelt und Geomatik / Dep. of Civil, Env. and Geomatic Eng.::02608 - Institut für Umweltingenieurwiss. / Institute of Environmental Engineering::03887 - Wang, Jing / Wang, Jing
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02115 - Dep. Bau, Umwelt und Geomatik / Dep. of Civil, Env. and Geomatic Eng.::02608 - Institut für Umweltingenieurwiss. / Institute of Environmental Engineering::03887 - Wang, Jing / Wang, Jing
ethz.date.deposited
2021-01-22T03:49:45Z
ethz.source
SCOPUS
ethz.eth
yes
en_US
ethz.availability
Metadata only
en_US
ethz.rosetta.installDate
2021-01-22T09:02:27Z
ethz.rosetta.lastUpdated
2022-03-29T04:55:30Z
ethz.rosetta.versionExported
true
ethz.COinS
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