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dc.contributor.author
Ganley, Robert
dc.contributor.author
Zeilhofer, Hanns-Ulrich
dc.contributor.editor
Fritzsch, Bernd
dc.date.accessioned
2021-02-17T16:45:47Z
dc.date.available
2021-01-26T07:31:12Z
dc.date.available
2021-02-17T16:45:47Z
dc.date.issued
2021
dc.identifier.isbn
978-0-12-805409-3
en_US
dc.identifier.other
10.1016/B978-0-12-809324-5.24133-3
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/465510
dc.description.abstract
GABA and glycine are the fast inhibitory neurotransmitters in the spinal dorsal horn. They inhibit neuronal excitation by opening chloride channels on the somata and dendrites of intrinsic dorsal horn neurons, and on the spinal terminals of peripheral sensory neurons. They are released from interneurons and from neurons descending from higher CNS areas. They limit nociceptive input to the dorsal horn, control the output of dorsal horn projection neurons, and separate non-nociceptive signaling from nociceptive dorsal horn circuits. Peripheral inflammation and nerve injury reduce neuronal inhibition in the dorsal horn through various mechanisms that contribute to hyperalgesia and allodynia. © 2020 Elsevier Inc.
en_US
dc.language.iso
en
en_US
dc.publisher
Elsevier
en_US
dc.title
GABAergic and glycinergic inhibition in pain pathways
en_US
dc.type
Book Chapter
dc.date.published
2020-09-09
ethz.book.title
The Senses: A Comprehensive Reference
en_US
ethz.journal.volume
5
en_US
ethz.pages.start
220
en_US
ethz.pages.end
234
en_US
ethz.version.edition
2
en_US
ethz.publication.place
Amsterdam
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02020 - Dep. Chemie und Angewandte Biowiss. / Dep. of Chemistry and Applied Biosc.::02534 - Institut für Pharmazeutische Wiss. / Institute of Pharmaceutical Sciences::03742 - Zeilhofer, Hanns U. / Zeilhofer, Hanns U.
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02020 - Dep. Chemie und Angewandte Biowiss. / Dep. of Chemistry and Applied Biosc.::02534 - Institut für Pharmazeutische Wiss. / Institute of Pharmaceutical Sciences::03742 - Zeilhofer, Hanns U. / Zeilhofer, Hanns U.
en_US
ethz.date.deposited
2021-01-26T07:31:19Z
ethz.source
FORM
ethz.eth
yes
en_US
ethz.availability
Metadata only
en_US
ethz.rosetta.installDate
2021-02-17T16:45:59Z
ethz.rosetta.lastUpdated
2021-02-17T16:45:59Z
ethz.rosetta.versionExported
true
ethz.COinS
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