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dc.contributor.author
Kundra, Palni
dc.contributor.author
Rachmühl, Carole
dc.contributor.author
Lacroix, Christophe
dc.contributor.author
Geirnaert, Annelies
dc.date.accessioned
2021-03-05T14:03:01Z
dc.date.available
2021-01-28T07:49:52Z
dc.date.available
2021-01-28T13:20:03Z
dc.date.available
2021-03-05T14:03:01Z
dc.date.issued
2021-03
dc.identifier.issn
1613-4125
dc.identifier.issn
1613-4133
dc.identifier.other
10.1002/mnfr.201901271
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/466161
dc.description.abstract
In patients with inflammatory bowel diseases (IBD), dietary micronutrient intake is low and deficiencies are common. Besides the host, also the gut microbiota require micronutrients and low levels may disturb its functioning. Multi‐omics studies indeed detected shifts in micronutrient‐dependent microbial pathways in IBD. It is however not clear whether micronutrients may alleviate inflammation directly, by modulating the immune system, or also indirectly, by modulating the structure and function of the gut microbiota. The latter seems of particular interest, since the gut microbiota is one of the future therapeutic targets in IBD. A review of the most recent available literature on relevant micronutrients in context of IBD and gut microbiota was conducted. An overview per relevant micronutrient on its role on gut bacterial growth, metabolism and host–microbe interactions during gut inflammation is provided. Dietary micronutrients have potential to be part of future personalized microbiome‐targeted therapies in IBD, considering both the micronutrient status of the host and the gut microbiota. However, cohort studies together with integrated multi‐scale studies are needed to understand the mechanisms of micronutrient–microbiome–host interactions in IBD and to evaluate efficacy and safety of dietary micronutrient treatment strategies.
en_US
dc.language.iso
en
en_US
dc.publisher
Wiley‐VCH
en_US
dc.subject
Gut inflammation
en_US
dc.subject
IBD
en_US
dc.subject
Microbiome
en_US
dc.subject
Minerals
en_US
dc.subject
Vitamins
en_US
dc.title
Role of Dietary Micronutrients on Gut Microbial Dysbiosis and Modulation in Inflammatory Bowel Disease
en_US
dc.type
Journal Article
dc.date.published
2020-12-07
ethz.journal.title
Molecular Nutrition & Food Research
ethz.journal.volume
65
en_US
ethz.journal.issue
5
en_US
ethz.pages.start
1901271
en_US
ethz.size
15 p.
en_US
ethz.grant
Deciphering the role of vitamins B9 and B12 as modulators of the human gut microbiota
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
Weinheim
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02070 - Dep. Gesundheitswiss. und Technologie / Dep. of Health Sciences and Technology::02701 - Inst.f. Lebensmittelwiss.,Ernährung,Ges. / Institute of Food, Nutrition, and Health::03626 - Lacroix, Christophe / Lacroix, Christophe
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02070 - Dep. Gesundheitswiss. und Technologie / Dep. of Health Sciences and Technology::02701 - Inst.f. Lebensmittelwiss.,Ernährung,Ges. / Institute of Food, Nutrition, and Health::03626 - Lacroix, Christophe / Lacroix, Christophe
en_US
ethz.grant.agreementno
179307
ethz.grant.fundername
SNF
ethz.grant.funderDoi
10.13039/501100001711
ethz.grant.program
Projekte Lebenswissenschaften
ethz.date.deposited
2021-01-28T07:50:01Z
ethz.source
FORM
ethz.eth
yes
en_US
ethz.availability
Metadata only
en_US
ethz.rosetta.installDate
2021-03-05T14:03:12Z
ethz.rosetta.lastUpdated
2022-03-29T05:38:48Z
ethz.rosetta.versionExported
true
ethz.COinS
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