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dc.contributor.author
Granata, Giuseppe
dc.contributor.author
Valle, Giacomo
dc.contributor.author
Di Iorio, Riccardo
dc.contributor.author
Iodice, Francesco
dc.contributor.author
Petrini, Francesco
dc.contributor.author
Strauss, Ivo
dc.contributor.author
D'Anna, Edoardo
dc.contributor.author
Iberite, Francesco
dc.contributor.author
Lauretti, Liverana
dc.contributor.author
Fernandez, Eduardo
dc.contributor.author
Romanello, Roberto
dc.contributor.author
Stieglitz, Thomas
dc.contributor.author
Raspopovic, Stanisa
dc.contributor.author
Calabresi, Paolo
dc.contributor.author
Micera, Silvestro
dc.contributor.author
Rossini, Paolo M.
dc.date.accessioned
2021-02-24T15:07:46Z
dc.date.available
2021-02-01T10:05:41Z
dc.date.available
2021-02-24T15:07:46Z
dc.date.issued
2020-10
dc.identifier.issn
1388-2457
dc.identifier.issn
1872-8952
dc.identifier.other
10.1016/j.clinph.2020.06.023
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/467023
dc.description.abstract
Objective To study motor cortex plasticity after a period of training with a new prototype of bidirectional hand prosthesis in three left trans-radial amputees, correlating these changes with the modification of Phantom Limb Pain (PLP) in the same period. Methods Each subject underwent a brain motor mapping with Transcranial Magnetic Stimulation (TMS) and PLP evaluation with questionnaires during a six-month training with a prototype of bidirectional hand prosthesis. Results The baseline motor maps showed in all three amputees a smaller area of muscles representation of the amputated side compared to the intact limb. After training, there was a partial reversal of the baseline asymmetry. The two subjects affected by PLP experienced a statistically significant reduction of pain. Conclusions Two apparently opposite findings, the invasion of the “deafferented” cortex by neighbouring areas and the “persistence” of neural structures after amputation, could vary according to different target used for measurement. Our results do not support a correlation between PLP and motor cortical changes. Significance The selection of the target and of the task is essential for studies investigating motor brain plasticity. This study boosts against a direct and unique role of motor cortical changes on PLP genesis. © 2020 Published by Elsevier B.V.
en_US
dc.language.iso
en
en_US
dc.publisher
Elsevier
en_US
dc.subject
Hand amputation
en_US
dc.subject
Motor map
en_US
dc.subject
Bidirectional hand prosthesis
en_US
dc.subject
Robotic hand
en_US
dc.subject
Brain plasticity
en_US
dc.subject
Phantom limb pain
en_US
dc.title
Cortical plasticity after hand prostheses use: Is the hypothesis of deafferented cortex “invasion” always true?
en_US
dc.type
Journal Article
dc.date.published
2020-07-15
ethz.journal.title
Clinical Neurophysiology
ethz.journal.volume
131
en_US
ethz.journal.issue
10
en_US
ethz.journal.abbreviated
Clin Neurophysiol
ethz.pages.start
2341
en_US
ethz.pages.end
2348
en_US
ethz.publication.place
Amsterdam
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02070 - Dep. Gesundheitswiss. und Technologie / Dep. of Health Sciences and Technology::09632 - Raspopovic, Stanisa / Raspopovic, Stanisa
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02070 - Dep. Gesundheitswiss. und Technologie / Dep. of Health Sciences and Technology::09632 - Raspopovic, Stanisa / Raspopovic, Stanisa
en_US
ethz.date.deposited
2021-02-01T10:05:48Z
ethz.source
FORM
ethz.eth
yes
en_US
ethz.availability
Metadata only
en_US
ethz.rosetta.installDate
2021-02-24T15:07:57Z
ethz.rosetta.lastUpdated
2021-02-24T15:07:57Z
ethz.rosetta.versionExported
true
ethz.COinS
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