Current Aspects of Corrinoid Synthesis

Abstract

This lecture deals essentially with three current aspects of corrinoid synthesis: first, with the present state of the work towards a synthesis of vitamin B12 as it is proceedig in the ETH laboratories in collaboration with Prodessor Woodward's group at Harvard; second, with the feed back this B12 work has been - and still is - exerting on the general field of corrin synthesis; and finally, with one of the main lessons synthetic corrin chemistry has taught us, namely, the powerful potentials of the concept of template controlled synthesis.