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Myeloproliferative neoplasms (MPNs) are hematological malignancies caused by somatic mutations originating from a single hematopoietic stem cell (HSC). In this issue of Cell Stem Cell, Van Egeren et al. (2021) used whole-genome sequencing of hematopoietic colonies to reconstruct the clonal history and time of acquisition of the disease-initiating gene mutation. © 2021 Elsevier Show more
Journal / seriesCell Stem Cell
Pages / Article No.
Organisational unit03584 - Bonhoeffer, Sebastian / Bonhoeffer, Sebastian
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