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dc.contributor.author
Burkard, Theresa
dc.contributor.author
Rauch, Marlene
dc.contributor.author
Jick, Susan S.
dc.contributor.author
Meier, Christoph R.
dc.date.accessioned
2021-07-06T15:27:47Z
dc.date.available
2021-06-19T03:04:43Z
dc.date.available
2021-07-06T15:27:47Z
dc.date.issued
2021-07
dc.identifier.issn
1053-8569
dc.identifier.issn
1099-1557
dc.identifier.other
10.1002/pds.5221
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/490441
dc.description.abstract
Objectives To assess completeness and validity of bariatric surgery codes in the UK Clinical Practice Research Datalink (CPRD) GOLD compared with Hospital Episodes Statistics (HES). Methods We conducted a validation study among patients in the UK-based CPRD GOLD with linkage to HES (1998 to 2017). Since the same surgery codes are used for bariatric and other gastrointestinal surgery we assessed code distribution patterns used in patients with bariatric versus other gastrointestinal surgery by presence of other conditions such as obesity and gastrointestinal cancer. We developed algorithms to identify bariatric surgery and calculated validity measures (ie, positive/negative predictive value [PPV/NPV], sensitivity, and specificity) of each in CPRD GOLD compared with HES (gold standard). Results Among 7 357 007 available patients we identified 10 190 patients who had a total of 14 046 potential bariatric surgery codes in CPRD GOLD and/or HES. Surgery code patterns differed between bariatric surgery and assumed other gastrointestinal surgery. The sensitivity of CPRD GOLD bariatric surgery coding improved from an overall of 56% to 69–71% when applying stricter algorithms (ie, in obese patients or obese, gastrointestinal disease/complication free patients) but PPVs remained at 53%–55%. NPVs and specificities of CPRD GOLD bariatric surgery coding achieved ≥99.8% for all algorithms. Conclusion Our results suggest that using CPRD GOLD and HES data and a wide selection of surgery codes will result in the most complete and accurate capture of bariatric surgery events. Validity measures of CPRD GOLD bariatric surgery codes were identical in obese patients and more restrictive populations.
en_US
dc.language.iso
en
en_US
dc.publisher
Wiley
en_US
dc.subject
Bariatric surgery
en_US
dc.subject
CPRD
en_US
dc.subject
epidemiology
en_US
dc.subject
HES
en_US
dc.subject
obesity
en_US
dc.subject
pharmacoepidemiology
en_US
dc.subject
validation
en_US
dc.title
Validity of bariatric surgery codes in the UK Clinical Practice Research Datalink (CPRD) GOLD compared with Hospital Episodes Statistics
en_US
dc.type
Journal Article
dc.date.published
2021-03-06
ethz.journal.title
Pharmacoepidemiology and Drug Safety
ethz.journal.volume
30
en_US
ethz.journal.issue
7
en_US
ethz.pages.start
858
en_US
ethz.pages.end
867
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
Chichester
en_US
ethz.publication.status
published
en_US
ethz.relation.isPartOf
10.1002/pds.4864
ethz.date.deposited
2021-06-19T03:04:46Z
ethz.source
SCOPUS
ethz.eth
yes
en_US
ethz.availability
Metadata only
en_US
ethz.rosetta.installDate
2021-07-06T15:28:26Z
ethz.rosetta.lastUpdated
2021-07-06T15:28:26Z
ethz.rosetta.versionExported
true
ethz.COinS
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