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dc.contributor.author
Höller, Christian
dc.contributor.author
Schnoering, Gabriel
dc.contributor.author
Eghlidi, Hadi
dc.contributor.author
Suomalainen, Maarit
dc.contributor.author
Greber, Urs F.
dc.contributor.author
Poulikakos, Dimos
dc.date.accessioned
2021-07-08T10:57:01Z
dc.date.available
2021-07-07T20:24:08Z
dc.date.available
2021-07-08T10:57:01Z
dc.date.issued
2021-06-30
dc.identifier.issn
2375-2548
dc.identifier.other
10.1126/sciadv.abd8758
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/493443
dc.identifier.doi
10.3929/ethz-b-000493443
dc.description.abstract
Understanding and controlling the individual behavior of nanoscopic matter in liquids, the environment in which many such entities are functioning, is both inherently challenging and important to many natural and man-made applications. Here, we transport individual nano-objects, from an assembly in a biological ionic solution, through a nanochannel network and confine them in electrokinetic nanovalves, created by the collaborative effect of an applied ac electric field and a rationally engineered nanotopography, locally amplifying this field. The motion of so-confined fluorescent nano-objects is tracked, and its kinetics provides important information, enabling the determination of their particle diffusion coefficient, hydrodynamic radius, and electrical conductivity, which are elucidated for artificial polystyrene nanospheres and subsequently for sub–100-nm conjugated polymer nanoparticles and adenoviruses. The on-chip, individual nano-object resolution method presented here is a powerful approach to aid research and development in broad application areas such as medicine, chemistry, and biology.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
American Association for the Advancement of Science
en_US
dc.rights.uri
http://creativecommons.org/licenses/by-nc/4.0/
dc.title
On-chip transporting arresting and characterizing individual nano-objects in biological ionic liquids
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution-NonCommercial 4.0 International
ethz.journal.title
Science Advances
ethz.journal.volume
7
en_US
ethz.journal.issue
27
en_US
ethz.journal.abbreviated
Sci Adv
ethz.pages.start
eabd8758
en_US
ethz.size
8 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
Washington, DC
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02130 - Dep. Maschinenbau und Verfahrenstechnik / Dep. of Mechanical and Process Eng.::02668 - Inst. f. Energie- und Verfahrenstechnik / Inst. Energy and Process Engineering::03462 - Poulikakos, Dimos / Poulikakos, Dimos
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02130 - Dep. Maschinenbau und Verfahrenstechnik / Dep. of Mechanical and Process Eng.::02668 - Inst. f. Energie- und Verfahrenstechnik / Inst. Energy and Process Engineering::03462 - Poulikakos, Dimos / Poulikakos, Dimos
en_US
ethz.date.deposited
2021-07-07T20:24:14Z
ethz.source
FORM
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2021-07-08T10:57:08Z
ethz.rosetta.lastUpdated
2021-07-08T10:57:08Z
ethz.rosetta.exportRequired
true
ethz.rosetta.versionExported
true
ethz.COinS
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