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dc.contributor.author
Osanlouy, Mahyar
dc.contributor.author
Kuster, Niels
dc.contributor.author
Neufeld, Esra
dc.contributor.author
et al.
dc.date.accessioned
2021-07-19T09:58:07Z
dc.date.available
2021-07-19T02:28:52Z
dc.date.available
2021-07-19T09:58:07Z
dc.date.issued
2021-06
dc.identifier.issn
1664-042X
dc.identifier.other
10.3389/fphys.2021.693735
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/495656
dc.identifier.doi
10.3929/ethz-b-000495656
dc.description.abstract
The Data and Resource Center (DRC) of the NIH-funded SPARC program is developing databases, connectivity maps, and simulation tools for the mammalian autonomic nervous system. The experimental data and mathematical models supplied to the DRC by the SPARC consortium are curated, annotated and semantically linked via a single knowledgebase. A data portal has been developed that allows discovery of data and models both via semantic search and via an interface that includes Google Map-like 2D flatmaps for displaying connectivity, and 3D anatomical organ scaffolds that provide a common coordinate framework for cross-species comparisons. We discuss examples that illustrate the data pipeline, which includes data upload, curation, segmentation (for image data), registration against the flatmaps and scaffolds, and finally display via the web portal, including the link to freely available online computational facilities that will enable neuromodulation hypotheses to be investigated by the autonomic neuroscience community and device manufacturers.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
Frontiers Research Foundation
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject
SPARC
en_US
dc.subject
autonomic nervous system
en_US
dc.subject
FAIR
en_US
dc.subject
data curation
en_US
dc.subject
data annotation
en_US
dc.subject
neural mapping
en_US
dc.subject
knowledge management
en_US
dc.subject
computational life sciences
en_US
dc.title
The SPARC DRC: Building a Resource for the Autonomic Nervous System Community
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 4.0 International
dc.date.published
2021-06-24
ethz.journal.title
Frontiers in Physiology
ethz.journal.volume
12
en_US
ethz.journal.abbreviated
Front Physiol
ethz.pages.start
693735
en_US
ethz.size
18 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
Lausanne
en_US
ethz.publication.status
published
en_US
ethz.date.deposited
2021-07-19T02:29:00Z
ethz.source
WOS
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2021-07-19T09:58:14Z
ethz.rosetta.lastUpdated
2022-03-29T10:29:16Z
ethz.rosetta.versionExported
true
ethz.COinS
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