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dc.contributor.author
Cardona, Albert
dc.contributor.author
Saalfeld, Stephan
dc.contributor.author
Schindelin, Johannes
dc.contributor.author
Arganda-Carreras, Ignacio
dc.contributor.author
Preibisch, Stephan
dc.contributor.author
Longair, Mark
dc.contributor.author
Tomancak, Pavel
dc.contributor.author
Hartenstein, Volker
dc.contributor.author
Douglas, Rodney J.
dc.date.accessioned
2018-09-20T10:37:07Z
dc.date.available
2017-06-10T02:05:53Z
dc.date.available
2018-09-20T10:37:07Z
dc.date.issued
2012-06-19
dc.identifier.issn
1932-6203
dc.identifier.other
10.1371/journal.pone.0038011
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/51246
dc.identifier.doi
10.3929/ethz-b-000051246
dc.description.abstract
A key challenge in neuroscience is the expeditious reconstruction of neuronal circuits. For model systems such as Drosophila and C. elegans, the limiting step is no longer the acquisition of imagery but the extraction of the circuit from images. For this purpose, we designed a software application, TrakEM2, that addresses the systematic reconstruction of neuronal circuits from large electron microscopical and optical image volumes. We address the challenges of image volume composition from individual, deformed images; of the reconstruction of neuronal arbors and annotation of synapses with fast manual and semi-automatic methods; and the management of large collections of both images and annotations. The output is a neural circuit of 3d arbors and synapses, encoded in NeuroML and other formats, ready for analysis.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
Public Library of Science
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/3.0/
dc.title
TrakEM2 Software for Neural Circuit Reconstruction
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 3.0 Unported
ethz.journal.title
PLoS ONE
ethz.journal.volume
7
en_US
ethz.journal.issue
6
en_US
ethz.journal.abbreviated
PLoS ONE
ethz.pages.start
e38011
en_US
ethz.size
8 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.wos
ethz.identifier.nebis
006206116
ethz.publication.status
published
en_US
ethz.date.deposited
2017-06-10T02:06:28Z
ethz.source
ECIT
ethz.identifier.importid
imp59364f64b425588236
ethz.ecitpid
pub:83591
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2017-07-12T18:22:13Z
ethz.rosetta.lastUpdated
2018-09-20T10:37:10Z
ethz.rosetta.exportRequired
true
ethz.rosetta.versionExported
true
ethz.COinS
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