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dc.contributor.author
Giovannelli, Anna C.
dc.contributor.author
Safai, Sairos
dc.contributor.author
Meer, David
dc.contributor.author
Weber, Damien C.
dc.contributor.author
Lomax, Antony J.
dc.contributor.author
Fattori, Giovanni
dc.date.accessioned
2021-11-25T12:27:48Z
dc.date.available
2021-11-25T10:52:46Z
dc.date.available
2021-11-25T12:27:48Z
dc.date.issued
2021-11
dc.identifier.uri
http://hdl.handle.net/20.500.11850/516849
dc.identifier.doi
10.3929/ethz-b-000516849
dc.description.abstract
Background: Tumour tracking is particularly challenging to realise when it comes to proton therapy. The difficulty of assessing anatomical changes reliably enough to offset the treatment settings on-the-fly, while taking into account the finite range of particles, is beyond the current capabilities of beam delivery and image guidance technologies. Methods: To implement fast range corrections, momentum acceptance (±0.6% dp/p) and global achromaticity of PSI Gantry2 has been exploited. Using a standard upstream degrader, the energy can be modulated around the mean value of the acceptance band without tuning the beamline magnets, overcoming the major source of dead-time in conventional treatments delivery. Being acceptance limited, such ultra-fast energy changes can only be of small magnitude, ~2mm WER. Therefore, at an early stage of planning, 4DCT images of the patient are used to generate a scan-path with dose spots sorted by energy, including tracking offsets, which can synchronized during delivery to the patient motion. Results: Beam properties within the momentum acceptance of our facility have been characterized between 150 MeV and 230 MeV. Using dedicated correction models for fine range control and compensation of beam intensity losses, a median energy switching time of 27ms could be achieved. Moreover, spot position errors in the transversal plane were below 1 mm across the 18x12 cm scan range. Conclusions: Rapid adaptation of beam range is essential to deliver tumour tracking plan following patients’ breathing. Fast energy modulation can be realized within the beamline acceptance preserving clinical level beam quality.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.rights.uri
http://rightsstatements.org/page/InC-NC/1.0/
dc.title
Exploring beamline momentum acceptance of a medical gantry to deliver optimized tumour tracking plans
en_US
dc.type
Conference Poster
dc.rights.license
In Copyright - Non-Commercial Use Permitted
ethz.size
1 p. accepted version
en_US
ethz.event
4D Treatment Workshop for Particle Therapy
en_US
ethz.event.location
Delft, Netherlands
en_US
ethz.event.date
November 12–13, 2021
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02010 - Dep. Physik / Dep. of Physics
en_US
ethz.date.deposited
2021-11-25T10:52:52Z
ethz.source
FORM
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2021-11-25T12:28:00Z
ethz.rosetta.lastUpdated
2022-03-29T16:08:57Z
ethz.rosetta.versionExported
true
ethz.COinS
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