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dc.contributor.author
Hovinen, Topi
dc.contributor.author
Korkalo, Liisa
dc.contributor.author
Freese, Riitta
dc.contributor.author
Skaffari, Essi
dc.contributor.author
Isohanni, Pirjo
dc.contributor.author
Niemi, Mikko
dc.contributor.author
Nevalainen, Jaakko
dc.contributor.author
Gylling, Helena
dc.contributor.author
Zamboni, Nicola
dc.contributor.author
Erkkola, Maijaliisa
dc.contributor.author
Suomalainen, Anu
dc.date.accessioned
2022-01-19T08:47:51Z
dc.date.available
2022-01-19T08:47:51Z
dc.date.issued
2021-02-05
dc.identifier.issn
1757-4676
dc.identifier.issn
1757-4684
dc.identifier.other
10.15252/emmm.202013492
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/526794
dc.identifier.doi
10.3929/ethz-b-000468144
dc.description.abstract
Vegan diets are gaining popularity, also in families with young children. However, the effects of strict plant-based diets on metabolism and micronutrient status of children are unknown. We recruited 40 Finnish children with a median age 3.5 years-vegans, vegetarians, or omnivores from same daycare centers-for a cross-sectional study. They enjoyed nutritionist-planned vegan or omnivore meals in daycare, and the full diets were analyzed with questionnaires and food records. Detailed analysis of serum metabolomics and biomarkers indicated vitamin A insufficiency and border-line sufficient vitamin D in all vegan participants. Their serum total, HDL and LDL cholesterol, essential amino acid, and docosahexaenoic n-3 fatty acid (DHA) levels were markedly low and primary bile acid biosynthesis, and phospholipid balance was distinct from omnivores. Possible combination of low vitamin A and DHA status raise concern for their visual health. Our evidence indicates that (i) vitamin A and D status of vegan children requires special attention; (ii) dietary recommendations for children cannot be extrapolated from adult vegan studies; and (iii) longitudinal studies on infant-onset vegan diets are warranted.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
Wiley
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject
development
en_US
dc.subject
metabolism
en_US
dc.subject
nutrition
en_US
dc.subject
vegan
en_US
dc.subject
vitamin
en_US
dc.title
Vegan diet in young children remodels metabolism and challenges the statuses of essential nutrients
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 4.0 International
dc.date.published
2021-01-20
ethz.journal.title
EMBO Molecular Medicine
ethz.journal.volume
13
en_US
ethz.journal.issue
2
en_US
ethz.journal.abbreviated
EMBO Mol Med
ethz.pages.start
e13492
en_US
ethz.size
12 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
Weinheim
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02030 - Dep. Biologie / Dep. of Biology::02538 - Institut für Molekulare Systembiologie / Institute for Molecular Systems Biology::08839 - Zamboni, Nicola (Tit.-Prof.)
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02030 - Dep. Biologie / Dep. of Biology::02538 - Institut für Molekulare Systembiologie / Institute for Molecular Systems Biology::08839 - Zamboni, Nicola (Tit.-Prof.)
ethz.date.deposited
2021-02-06T03:42:02Z
ethz.source
BATCH
ethz.source
WOS
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2022-01-19T08:48:04Z
ethz.rosetta.lastUpdated
2022-03-29T17:41:00Z
ethz.rosetta.versionExported
true
dc.identifier.olduri
http://hdl.handle.net/20.500.11850/525509
dc.identifier.olduri
http://hdl.handle.net/20.500.11850/468144
ethz.COinS
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