Five Hours Total Sleep Deprivation Does Not Affect CA1 Dendritic Length or Spine Density
dc.contributor.author
Brodin, Alvin T.S.
dc.contributor.author
Gabulya, Sarolta
dc.contributor.author
Wellfelt, Katrin
dc.contributor.author
Karlsson, Tobias E.
dc.date.accessioned
2022-04-22T13:29:25Z
dc.date.available
2022-04-15T08:25:17Z
dc.date.available
2022-04-22T13:29:25Z
dc.date.issued
2022-03-14
dc.identifier.issn
1663-3563
dc.identifier.other
10.3389/fnsyn.2022.854160
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/542514
dc.identifier.doi
10.3929/ethz-b-000542514
dc.description.abstract
Sleep is essential for long term memory function. However, the neuroanatomical consequences of sleep loss are disputed. Sleep deprivation has been reported to cause both decreases and increases of dendritic spine density. Here we use Thy1-GFP expressing transgenic mice to investigate the effects of acute sleep deprivation on the dendritic architecture of hippocampal CA1 pyramidal neurons. We found that 5 h of sleep deprivation had no effect on either dendritic length or dendritic spine density. Our work suggests that no major neuroanatomical changes result from a single episode of sleep deprivation.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
Frontiers Media
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject
sleep deprivation
en_US
dc.subject
plasticity
en_US
dc.subject
spines
en_US
dc.subject
dendrite
en_US
dc.subject
hippocampus
en_US
dc.title
Five Hours Total Sleep Deprivation Does Not Affect CA1 Dendritic Length or Spine Density
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 4.0 International
ethz.journal.title
Frontiers in Synaptic Neuroscience
ethz.journal.volume
14
en_US
ethz.journal.abbreviated
Front. Synaptic Neurosci.
ethz.pages.start
854160
en_US
ethz.size
7 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
Lausanne
ethz.publication.status
published
en_US
ethz.date.deposited
2022-04-15T08:25:29Z
ethz.source
SCOPUS
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2022-04-22T13:29:46Z
ethz.rosetta.lastUpdated
2024-02-02T16:44:19Z
ethz.rosetta.versionExported
true
ethz.COinS
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Journal Article [133572]