Seeberger, Peter H.
- Journal Article
Rights / licenseCreative Commons Attribution 2.0 Generic
Sialic acid-containing glycans play a major role in cell-surface interactions with external partners such as cells and viruses. Straightforward access to sialosides is required in order to study their biological functions on a molecular level. Here, automated oligosaccharide synthesis was used to facilitate the preparation of this class of biomolecules. Our strategy relies on novel sialyl α-(2→3) and α-(2→6) galactosyl imidates, which, used in combination with the automated platform, provided rapid access to a small library of conjugation-ready sialosides of biological relevance. Show more
Journal / seriesBeilstein Journal of Organic Chemistry
Pages / Article No.
PublisherBeilstein-Institut zur Förderung der Chemischen Wissenschaften
SubjectAutomated synthesis; Disaccharide building blocks; Solid-phase; Synthesis; Sialic acid; Sialosides
Organisational unit03811 - Leroux, Jean-Christophe / Leroux, Jean-Christophe
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