Primate pre-arcuate cortex actively maintains persistent representations of saccades from plans to outcomes
dc.contributor.author
Calangiu, Ioana
dc.contributor.author
Kollmorgen, Sepp
dc.contributor.author
Reppas, John
dc.contributor.author
Mante, Valerio
dc.date.accessioned
2023-02-06T10:30:01Z
dc.date.available
2023-01-31T16:11:38Z
dc.date.available
2023-02-06T10:30:01Z
dc.date.issued
2022-09-27
dc.identifier.other
10.1101/2022.09.26.509463
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/596331
dc.identifier.doi
10.3929/ethz-b-000596331
dc.description.abstract
Dorso-lateral prefrontal cortex is thought to contribute to adaptive behavior by integrating temporally dispersed, behaviorally-relevant factors. Past work has revealed a variety of neural representations preceding actions, which are involved in internal processes like planning, working memory and covert attention. Task-related activity following actions has often been reported, but so far lacks a clear interpretation. We leveraged modified versions of classic oculomotor paradigms and population recordings to show that post-saccadic activity is a dominant signal in dorso-lateral prefrontal cortex that is distinct from pre-saccadic activity. Unlike pre-saccadic activity, post-saccadic activity occurs after each saccade, although its strength and duration are modulated by task context and expected rewards. In contrast to representations preceding actions, which appear to be mixed randomly across neurons, post-saccadic activity results in representations that are highly structured at the single-neuron and population level. Overall, the properties of post-saccadic activity are consistent with those of an action memory, an internal process with a possible role in learning and updating spatial representations.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
Cold Spring Harbor Laboratory
en_US
dc.rights.uri
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.title
Primate pre-arcuate cortex actively maintains persistent representations of saccades from plans to outcomes
en_US
dc.type
Working Paper
dc.rights.license
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
ethz.journal.title
bioRxiv
ethz.size
49 p.
en_US
ethz.publication.place
Cold Spring Harbor, NY
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02140 - Dep. Inf.technologie und Elektrotechnik / Dep. of Inform.Technol. Electrical Eng.::02533 - Institut für Neuroinformatik / Institute of Neuroinformatics::09776 - Mante, Valerio / Mante, Valerio
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02140 - Dep. Inf.technologie und Elektrotechnik / Dep. of Inform.Technol. Electrical Eng.::02533 - Institut für Neuroinformatik / Institute of Neuroinformatics::09776 - Mante, Valerio / Mante, Valerio
en_US
ethz.date.deposited
2023-01-31T16:11:39Z
ethz.source
FORM
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2023-02-06T10:30:02Z
ethz.rosetta.lastUpdated
2024-02-02T19:41:18Z
ethz.rosetta.versionExported
true
ethz.COinS
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Working Paper [5738]